The structure and function of peripheral nerves can be affected by a range of conditions with
severe consequences in these patients. Currently, there are several surgical techniques …

Despite the inherent capability for axonal regeneration, recovery following severe peripheral
nerve injury remains unpredictable and often very poor. Surgeons typically use autologous …

Introduction: Processed nerve allografts offer a promising alternative to nerve autografts in
the surgical management of peripheral nerve injuries where short deficits exist. Methods …

Repair of large nerve defects with acellular nerve allografts (ANAs) is an appealing
alternative to autografting and allotransplantation. ANAs have been shown to be similar to …

Sensory nerve autografting is the standard of care for injuries resulting in a nerve gap.
Recent work demonstrates superior regeneration with motor nerve grafts. Improved …

Quantitative histomorphometry is the current gold standard for objective measurement of
nerve architecture and its components. Many methods still in use rely heavily upon manual …

Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal
regeneration across long defects (> 3 cm). Causes for this deficiency are poorly understood …

Peripheral nerve damage results in the loss of sensorimotor and autonomic functions, which
is a significant burden to patients. Furthermore, nerve injuries greater than the limiting gap …

Background: An effective alternative to nerve autograft is needed to minimize morbidity and
solve limited-availability issues. We hypothesized that the use of processed allografts and …

Background A significant barrier to organ transplantation is the cellular rejection that occurs
and mediated by antibodies, T cells, and innate immune cells. This study was aimed to …