Enthusiasm for mining advanced biofuels from microbial hosts has increased remarkably in
recent years. Isoprenoids are one of the highly diverse groups of secondary metabolites and …

Recent years have seen a remarkable increase in the nonnatural production of terpenoids
by the microbial route. This is due to the advancements in synthetic biology tools and …

Background Heterologous protein production in Escherichia coli often suffers from
bottlenecks such as proteolytic degradation, complex purification procedures and toxicity …

Background Recombinant proteins are routinely overexpressed in metabolic engineering. It
is well known that some over-expressed heterologous recombinant enzymes are insoluble …

Enthusiasm for mining isoprenoid-based flavors, pharmaceuticals, and nutraceuticals from
GRAS (Generally Regarded as Safe) status microbial hosts has increased in the past few …

Recent years have seen a remarkable increase in the global interest for mining isoprenoid-
based fine-chemicals and nutraceuticals from GRAS (Generally regarded as Safe) status …

Toxin–antitoxin (TA) systems are found on both chromosomes and plasmids. These systems
are unique in that they can confer both fatal and protective effects on bacterial cells—a …

Abstract In Escherichia coli, the Twin-arginine translocation (Tat) pathway secretes a set of
folded proteins with important physiological functions to the periplasm and outer membrane …

Nature has evolved several mechanisms to detoxify intracellular protein aggregates that
arise upon proteotoxic challenges. These include the controlled deposition of misfolded …

In situ capacitance sensing is shown to be capable of monitoring critical morphological
changes in industrial cultures by analyzing the sensor's frequency spectrum. Scanning the …