Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Polyamine‐based vectors offer many advantages for gene therapy, but they are hampered
by a limited knowledge on their biological fate and efficacy for nucleic acid delivery. The 18F …

Designing effective drug nanocarriers that are easy to synthesize, robust, and nontoxic is a
significant challenge in nanomedicine. Polyamine-multivalent molecule nanocomplexes are …

A deeper knowledge on the formation and biological fate of polymer based gene vectors is
needed for their translation into therapy. Here, polyplexes of polyethyleneimine (PEI) and …

N-Acetylgalactosamine-6-sulfatase (GALNS) is an enzyme whose deficiency is related to the
lysosomal storage disease Morquio A. For the development of effective therapeutic …

Hypothesis Renal calculi (kidney stones) are mainly made by calcium oxalate and can
cause different complications including malfunction of the kidney. The most important urinary …

Radiolabeling and nuclear imaging techniques are used to investigate the biodistribution
patterns of the soft and hard protein corona around poly (lactic‐co‐glycolic acid) …

Hypothesis Lipopeptides synthesized from the Nucleolar Targeting Peptide (NrTP6) with
one, two or four dodecanoic fatty acid (FA) chains, display large head to tail volumes, which …

The blood enzyme glutamate oxaloacetate transaminase (GOT) has been postulated as an
effective therapeutic to protect the brain during stroke. To demonstrate its potential clinical …