Lipids and bariatric procedures part 1 of 2: scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and obesity …

HE Bays, PH Jones, TA Jacobson, DE Cohen… - Journal of clinical …, 2016 - Elsevier
Bariatric procedures often improve lipid levels in patients with obesity. This 2 part scientific
statement examines the potential lipid benefits of bariatric procedures and represents the …

Epicardial and pericardial adipose tissues are associated with reduced diastolic and systolic function in type 2 diabetes

RH Christensen, CS Hansen… - Diabetes, Obesity …, 2019 - Wiley Online Library
The aim of this study was to investigate the association of epicardial (EAT) and pericardial
(PAT) adipose tissues with myocardial function in type 2 diabetes (T2D). EAT and PAT were …

Postmenopausal women with greater paracardial fat have more coronary artery calcification than premenopausal women: the Study of Women's Health Across the …

SR El Khoudary, KJ Shields, I Janssen… - Journal of the …, 2017 - Am Heart Assoc
Background Volumes of paracardial adipose tissue (PAT) and epicardial adipose tissue
(EAT) are greater after menopause. Interestingly, PAT but not EAT is associated with …

Effects of hormone therapy on heart fat and coronary artery calcification progression: secondary analysis from the KEEPS trial

SR El Khoudary, Q Zhao, V Venugopal… - Journal of the …, 2019 - Am Heart Assoc
Background Heart fats (epicardial and paracardial adipose tissue [PAT]) are greater after
menopause. Endogenous estrogen may regulate these fat depots. We evaluated the …

Melatonin efficacy in obese leptin-deficient mice heart

A Stacchiotti, G Favero, L Giugno, I Golic, A Korac… - Nutrients, 2017 - mdpi.com
Cardiomyocytes are particularly sensitive to oxidative damage due to the link between
mitochondria and sarcoplasmic reticulum necessary for calcium flux and contraction …

Cellular characterization of human epicardial adipose tissue: highly expressed PAPP‐A regulates insulin‐like growth factor I signaling in human cardiomyocytes

CA Conover, LK Bale, RL Frye… - Physiological reports, 2019 - Wiley Online Library
Little is known about the cellular biology of fat surrounding the human heart. In this study, we
obtained paired samples of epicardial fat, the visceral fat depot attached to the heart, and …

Characterization of mouse pericardial fat: regulation by PAPP-A

LK Bale, SA West, CA Conover - Growth Hormone & IGF Research, 2018 - Elsevier
Although implicated in cardiovascular disease, little is known about the fat surrounding the
heart. In humans, epicardial fat is the visceral fat depot of the heart, which directly contacts …

Three-dimensional micro computed tomography analysis of the lung vasculature and differential adipose proteomics in the Sugen/hypoxia rat model of pulmonary …

KJ Shields, K Verdelis, MJ Passineau… - Pulmonary …, 2016 - journals.sagepub.com
Pulmonary arterial hypertension (PAH) is a rare disease characterized by significant
vascular remodeling. The obesity epidemic has produced great interest in the relationship …

Unique genetic and histological signatures of mouse pericardial adipose tissue

A Al-Dibouni, R Gaspar, S Ige, S Boateng… - Nutrients, 2020 - mdpi.com
Obesity is a major risk factor for a plethora of metabolic disturbances including diabetes and
cardiovascular disease. Accumulating evidence is showing that there is an adipose tissue …

Plasminogen activator inhibitor-1 and pericardial fat in individuals with type 2 diabetes mellitus

O Bayomy, AD Rao, R Garg, A Vaidya… - … syndrome and related …, 2017 - liebertpub.com
Abstract Background: Plasminogen activator inhibitor-1 (PAI-1) is implicated in the
pathophysiology of cardiovascular disease (CVD) and increased in individuals with type 2 …