Chronic liver disease (CLD) and several related extrahepatic manifestations such as hepatic
osteodystrophy are associated with deficiency of vitamin D, which has therefore been …

Excessive alcohol consumption causes a wide spectrum of liver disease, ranging from
simple steatosis to severe forms of liver injury such as steatohepatitis, liver fibrosis, cirrhosis …

Alcoholic liver disease (ALD) is a major cause of acute and chronic liver disease worldwide.
The progressive nature of ALD is well described; however, the complex interactions under …

The function of micro RNA s (mi RNA s) during alcoholic liver disease (ALD) has recently
become of great interest in biological research. Studies have shown that ALD associated mi …

BACKGROUND Endoplasmic reticulum (ER) stress is an important mechanism in the
progression of chronic and acute liver diseases, especially in the progression and recovery …

Xanthohumol (XN), a prenylated chalcone from hops, has been reported to exhibit a variety
of health-beneficial effects. However, poor bioavailability may limit its application in the …

In modern toxicology, substantial efforts are undertaken to develop alternative solutions for
in vivo toxicity testing. The adverse outcome pathway (AOP) concept could facilitate …

Alcohol is one of the main causes of liver diseases, and the development of alcoholic liver
disease (ALD) treatment methods has been one of the hottest issues. For this purpose …

Background Hepatic stellate cell (HSC) differentiation/activation is central to liver fibrosis
and is innately linked to the immune response to liver injury. Exosomes (EXOs) are …

The demand for scaffolds comprised of natural materials such as collagen has increased in
recent years. However, many scaffolds rely on chemical or physical modifications in order to …