Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention

SS Hecht, DK Hatsukami - Nature Reviews Cancer, 2022 - nature.com
Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …

Tobacco harm reduction: past history, current controversies and a proposed approach for the future

DK Hatsukami, DM Carroll - Preventive medicine, 2020 - Elsevier
Tobacco harm reduction remains a controversial topic in tobacco control. Tobacco harm
reduction involves providing tobacco users who are unwilling or unable to quit using …

[HTML][HTML] A review of the evidence on cigarettes with reduced addictiveness potential

EC Donny, CM White - International Journal of Drug Policy, 2022 - Elsevier
Abstract Background In May 2018, the Secretariat for the World Health Organization
Framework Convention on Tobacco Control convened a meeting to discuss the potential for …

Electronic nicotine delivery systems: an updated policy statement from the American Association for Cancer Research and the American Society of Clinical Oncology

RS Herbst, D Hatsukami, D Acton, M Giuliani… - Clinical Cancer …, 2022 - AACR
Combustible tobacco use has reached historic lows, demonstrating the importance of
proven strategies to reduce smoking since publication of the 1964 Surgeon General's report …

Nicotine reduction in cigarettes: literature review and gap analysis

ML Berman, AM Glasser - Nicotine and Tobacco Research, 2019 - academic.oup.com
Abstract Background The US Food and Drug Administration (FDA) is considering reducing
nicotine levels in cigarettes to “minimally or non-addictive levels.” However, important …

The impact of reducing nicotine content on adolescent cigarette smoking and nicotine exposure: results from a randomized controlled trial

RN Cassidy, JW Tidey, KM Jackson… - Nicotine and …, 2023 - academic.oup.com
Introduction As the science base around the potential benefits of a reduced-nicotine
standard for cigarettes grows, information on the potential effects on adolescent smokers is a …

Effects of very low nicotine content cigarettes and nicotine vaping device characteristics on choices to smoke, vape, or abstain in early young adults

RN Cassidy, JW Tidey, MS Bello… - Nicotine and …, 2025 - academic.oup.com
Introduction A national nicotine reduction policy could reduce the public health toll of
smoking. However, reducing nicotine in cigarettes may lead to changes in the use of other …

Effects of very low nicotine content cigarettes on smoking across vulnerable populations

JW Tidey, LM Snell, SM Colby, RN Cassidy… - Preventive …, 2022 - Elsevier
There has been long-standing interest in a reduced-nicotine product standard for combusted
tobacco, which is within the regulatory purview of the Food and Drug Administration (FDA) …

Regulatory approaches and implementation of minimally addictive combusted products

DK Hatsukami, D Xu… - Nicotine and Tobacco …, 2022 - academic.oup.com
Introduction A joint meeting was held by the World Health Organization (WHO) and the
Convention Secretariat of the WHO Framework Convention on Tobacco Control to examine …

Research on youth and young adult tobacco use, 2013–2018, from the Food and Drug Administration–National Institutes of Health Tobacco Centers of Regulatory …

CL Perry, MLR Creamer, BW Chaffee… - Nicotine and …, 2020 - academic.oup.com
Abstract The Tobacco Regulatory Science Program is a collaborative research effort
between the National Institutes of Health (NIH) and the Food and Drug Administration (FDA) …