The interconnections between the microtubules and mitochondrial networks in cardiocerebrovascular diseases: implications for therapy

X Shi, X Jiang, C Chen, Y Zhang, X Sun - Pharmacological Research, 2022 - Elsevier
Microtubules, a highly dynamic cytoskeleton, participate in many cellular activities including
mechanical support, organelles interactions, and intracellular trafficking. Microtubule …

Ultrastructural characteristics of neuronal death and white matter injury in mouse brain tissues after intracerebral hemorrhage: coexistence of ferroptosis, autophagy …

Q Li, A Weiland, X Chen, X Lan, X Han… - Frontiers in …, 2018 - frontiersin.org
Although intracerebral hemorrhage (ICH) is a devastating disease worldwide, the pathologic
changes in ultrastructure during the acute and chronic phases of ICH are poorly described …

White matter injury and recovery after hypertensive intracerebral hemorrhage

S Zuo, P Pan, Q Li, Y Chen… - BioMed Research …, 2017 - Wiley Online Library
Hypertensive intracerebral hemorrhage (ICH) could very probably trigger white matter injury
in patients. Through the continuous study of white matter injury after hypertensive ICH, we …

Dexpramipexole attenuates white matter injury to facilitate locomotion and motor coordination recovery via reducing ferroptosis after intracerebral hemorrhage

B Wang, X Zhang, J Zhong, S Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
Deciphering the factors causing damage to white matter fiber bundles and exploring new
strategies to alleviate white matter injury (WMI) is a promising treatment to improve …

Taurine supplementation reduces neuroinflammation and protects against white matter injury after intracerebral hemorrhage in rats

H Zhao, J Qu, Q Li, M Cui, J Wang, K Zhang, X Liu… - Amino acids, 2018 - Springer
Intracerebral hemorrhage (ICH) initiates a neuroinflammatory cascade that contributes to
substantial neuronal damage and neurological deterioration. Taurine, an abundant amino …

Investigation and modulation of interleukin-6 following subarachnoid hemorrhage: targeting inflammatory activation for cerebral vasospasm

B Lucke-Wold, W Dodd, K Motwani, K Hosaka… - Journal of …, 2022 - Springer
Background Cerebral vasospasm (CV) can contribute to significant morbidity in
subarachnoid hemorrhage (SAH) patients. A key unknown is how CV induction is triggered …

Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage

JC Cai, W Liu, F Lu, WB Kong… - Experimental and …, 2018 - spandidos-publications.com
Resveratrol (RESV) improves histopathological and behavioral outcomes in diseases of the
central nervous system. However, to the best of our knowledge, there have been no studies …

P7C3‐A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD+/Sirt3 Pathway

Y Wu, Q Hu, X Wu, Y Cai, Y Zhang, Y Wu… - Oxidative Medicine …, 2023 - Wiley Online Library
Intracerebral hemorrhage (ICH) is lethal but lacks effective therapies. Nicotinamide adenine
dinucleotide (NAD+) is a central metabolite indispensable for a broader range of …

Ambroxol improves neuronal survival and reduces white matter damage through suppressing endoplasmic reticulum stress in microglia after intracerebral …

X Jiang, J Zhang, B Kou, C Zhang… - BioMed research …, 2020 - Wiley Online Library
Intracerebral hemorrhage (ICH) has been becoming a serious public health problem.
Pneumonia, occurring in 43% of all ICH patients, is a common complication heavily …

[PDF][PDF] Melatonin attenuates white matter injury via reducing oligodendrocyte apoptosis after subarachnoid hemorrhage in mice

D Liu, Y Dong, G Li, Z Zou, G Hao, H Feng… - Turk …, 2020 - turkishneurosurgery.org.tr
ABSTRACT AIM: To determine whether melatonin (MLT) mitigates white matter (WM) injury
by attenuating NOD-like receptor family pyrin domain-containing 3 (NLRP3)-associated …