Toxoplasma gondii causes fatal and debilitating brain and eye diseases. Medicines that are
currently used to treat toxoplasmosis commonly have toxic side effects and require …

Ocular toxoplasmosis (OT) is considered the most frequent form of infectious posterior
uveitis and is caused by the protozoan parasite Toxoplasma gondii. The resulting vision loss …

Globally, congenital toxoplasmosis remains a significant cause of morbidity and mortality,
and outbreaks of infection with T. gondii represent a significant, emerging public health …

Great successes have been achieved in developing small-molecule kinase inhibitors as
anticancer therapeutic agents. However, kinase deregulation plays essential roles not only …

The use of chemotherapeutic drugs is the main resource against clinical giardiasis due to
the lack of approved vaccines. Resistance of G. duodenalis to the most used drugs to treat …

Apicomplexan parasites have complex life cycles, frequently split between different hosts
and reliant on rapid responses as the parasites react to changing environmental conditions …

The protozoan Toxoplasma gondii, an obligate intracellular parasite, is an etiological agent
of human and animal toxoplasmosis. Treatment regimens for T. gondii-infected patients …

1. INTRODUCTION Nitrogen-containing heterocycles are widely distributed in nature and
essential for life, playing a vital role in the metabolism of all living cells. Among the many …

Open-access drug discovery provides a substantial resource for diseases primarily affecting
the poor and disadvantaged. The open-access Pathogen Box collection is comprised of …

The phylum Apicomplexa comprises a group of obligate intracellular parasites of broad
medical and agricultural significance, including Toxoplasma gondii and the malaria-causing …