Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Fungal infections pose a serious threat to human health and livelihoods. The number and
variety of clinically approved antifungal drugs is very limited, and the emergence and rapid …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

Due to their eukaryotic heritage, the differences between a fungal pathogen's molecular
makeup and its human host are small. Therefore, the discovery and subsequent …

Candida albicans represents one of the most common fungal pathogens. Due to its
increasing incidence and the poor efficacy of available antifungals, finding novel antifungal …

Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

One of the saprophytic fungi that contaminates crops with carcinogenic aflatoxins is
Aspergillus flavus. During pre-harvest and post-harvest, microbial produced bioactive …

The landscape of infectious fungal agents includes previously unidentified or rare
pathogens with the potential to cause unprecedented casualties in biodiversity, food …

Life-threatening invasive fungal infections represent an urgent threat to human health
worldwide. The limited set of antifungal drugs has critical constraints such as resistance …

Fungal infections are a universal problem and are routinely associated with high morbidity
and mortality rates in immunocompromised patients. Existing therapies comprise five …