Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Advanced injectable hydrogels for cartilage tissue engineering

S Zhu, Y Li, Z He, L Ji, W Zhang, Y Tong… - … in bioengineering and …, 2022 - frontiersin.org
The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Acellular tissue-engineered vascular grafts from polymers: Methods, achievements, characterization, and challenges

X Wang, V Chan, PR Corridon - Polymers, 2022 - mdpi.com
Extensive and permanent damage to the vasculature leading to different pathogenesis calls
for developing innovative therapeutics, including drugs, medical devices, and cell therapies …

Tissue-mimetic hybrid bioadhesives for intervertebral disc repair

X Li, Y Liu, L Li, R Huo, F Ghezelbash, Z Ma, G Bao… - Materials …, 2023 - pubs.rsc.org
Intervertebral disc (IVD) degeneration and herniation often necessitate surgical interventions
including a discectomy with or without a nucleotomy, which results in a loss of the normal …

Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy

AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …

Biohybrid magnetic microrobots: An intriguing and promising platform in biomedicine

S Zhu, Y Cheng, J Wang, G Liu, T Luo, X Li, S Yang… - Acta Biomaterialia, 2023 - Elsevier
Biohybrid magnetic microrobots (BMMs) have emerged as an exciting class of microrobots
and have been considered as a promising platform in biomedicine. Many microorganisms …

Nasal cartilage tissue engineering materials based on 3D bioprinting: Seed cells and dECM

W Jia, X Yang, Z Liu, L Sun, Z Shen, M Li, H Zhang… - Applied Materials …, 2024 - Elsevier
The nasal cartilage plays a crucial role in supporting the nose and facilitating respiration,
however has a limited regenerative capabilities once damaged. Nasal cartilage tissue …

Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends

N Ahmad, SNA Bukhari, MA Hussain, H Ejaz… - RSC …, 2024 - pubs.rsc.org
The prevention and treatment of microbial infections is an imminent global public health
concern due to the poor antimicrobial performance of the existing antimicrobial regime and …

Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel

Y Huang, M Sun, Z Lu, Q Zhong, M Tan… - Regenerative …, 2024 - academic.oup.com
Cartilage defects may lead to severe degenerative joint diseases. Tissue engineering based
on type I collagen hydrogel that has chondrogenic potential is ideal for cartilage repair …

Applications and prospects of different functional hydrogels in meniscus repair

P Jin, L Liu, X Chen, L Cheng, W Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
The meniscus is a kind of fibrous cartilage structure that serves as a cushion in the knee joint
to alleviate the mechanical load. It is commonly injured, but it cannot heal spontaneously …