Apart from its role in motor coordination, the importance of the cerebellum in cognitive and
affective processes has been recognized in the past few decades. Spinocerebellar ataxias …

The cerebellum is one-third the size of the cerebrum yet holds twice the number of neurons.
Historically, its sole function was thought to be in the calibration of smooth movements …

Abstract Spinocerebellar ataxia type 2 (SCA2) is a polyglutamine disorder caused by a
pathological expansion of CAG repeats in ATXN2 gene. SCA2 is accompanied by cerebellar …

Background Depression is a common comorbidity in spinocerebellar ataxias (SCAs) but its
association with ataxia progression is not well understood. Objectives To study the …

Recent advances in understanding dominant spinocerebellar ataxias from clinical and
genetic points of view - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

The discipline of affective neuroscience is concerned with the neural bases of emotion and
mood. The past decades have witnessed an explosion of research in affective neuroscience …

Expansion of CAG trinucleotide repeats in ATXN1 causes spinocerebellar ataxia type 1
(SCA1), a neurodegenerative disease that impairs coordination and cognition. While ATXN1 …

Spinocerebellar ataxias (SCAs) represent a large group of hereditary degenerative diseases
of the nervous system, in particular the cerebellum, and other systems that manifest with a …

Objective Cerebellar neurodegenerative disorders (CDs) are a heterogeneous group of
disorders. It is known that the cerebellum plays a role not only in motor, but also in cognitive …

The cerebellar cognitive affective syndrome scale (CCAS-S) was designed to detect specific
cognitive dysfunctions in cerebellar patients but is scarcely validated in spinocerebellar …