Recent advances of hyaluronan for skin delivery: From structure to fabrication strategies and applications

M Juhaščik, A Kováčik, G Huerta-Ángeles - Polymers, 2022 - mdpi.com
Hyaluronan (HA) plays a fundamental role in maintaining the homeostasis on skin health.
Furthermore, the effect of HA in skin inflammatory diseases is worth studying in the next …

Integration of terpesomes loaded Levocetrizine dihydrochloride gel as a repurposed cure for Methicillin-Resistant Staphylococcus aureus (MRSA)-Induced skin …

MM El-Naggar, MA El-Nabarawi, MH Teaima… - International Journal of …, 2023 - Elsevier
The intention of this work is to assess the repurposed antimicrobial impact of Levocetirizine
dihydrochloride (LVC), which is a well-known antihistaminic drug, in addition, to augment …

[HTML][HTML] A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds

S Dereiah, MU Ghori, BR Conway - Pharmaceutics, 2024 - mdpi.com
Background/Objectives: Spironolactone (SP), an aldosterone inhibitor widely used to treat
androgen-dependent disorders such as acne, hirsutism, and alopecia, has demonstrated …

Repurposing levocetirizine hydrochloride loaded into cationic ceramide/phospholipid composite (CCPCs) for management of alopecia: central composite design …

R Albash, RM El-Dahmy, MIA Hamed, KM Darwish… - Drug …, 2022 - Taylor & Francis
Levocetirizine hydrochloride (LVC) is an antihistaminic drug that is repurposed for the
treatment of alopecia. This investigation is targeted for formulating LVC into cationic …

Exploring the synergistic effect of bergamot essential oil with spironolactone loaded nano-phytosomes for treatment of acne vulgaris: In vitro optimization, in silico …

R Albash, NM Badawi, MIA Hamed, MH Ragaie… - Pharmaceuticals, 2023 - mdpi.com
The foremost target of the current work was to formulate and optimize a novel bergamot
essential oil (BEO) loaded nano-phytosomes (NPs) and then combine it with spironolactone …

Transdermal fluocinolone acetonide loaded decorated hyalurosomes cellulose acetate/polycaprolactone nanofibers mitigated Freund's adjuvant-induced rheumatoid …

SF ELhabal, MA El-Nabarawi, SO Hassanin… - Journal of …, 2024 - Springer
Purpose This study aimed to develop a transdermal delivery system for fluocinolone
acetonide (FLA), a corticosteroid used in treating inflammatory conditions like rheumatoid …

Metformin loaded zein polymeric nanoparticles to augment antitumor activity against Ehrlich carcinoma via activation of AMPK pathway: d-optimal design optimization …

Y Elmahboub, R Albash, M Magdy William, AH Rayan… - Molecules, 2024 - mdpi.com
Metformin (MET), an antidiabetic drug, is emerging as a promising anticancer agent. This
study was initiated to investigate the antitumor effects and potential molecular targets of MET …

[HTML][HTML] Topical delivery of extracted curcumin as curcumin loaded spanlastics anti-aging gel: Optimization using experimental design and ex-vivo evaluation

R El Hosary, MH Teaima, M El-Nabarawi… - Saudi Pharmaceutical …, 2024 - Elsevier
Objective This study aimed to extract and separate the organic coloring agent known as
Curcumin from the rhizomes of Curcuma longa, and then to create Spanlastics that were …

人羊膜上皮干细胞联合富血小板血浆对宫腔粘连大鼠纤维化因子, 炎症因子的作用.

王丽, 张梦婷, 陈阳, 魏琳… - Progress in Modern …, 2023 - search.ebscohost.com
摘要目的: 探究人羊膜上皮干细胞(hAECs) 联合富血小板血浆(PRP) 对宫腔粘连大鼠的治疗效果
, 为临床中优化宫腔粘连治疗方法理论基础. 方法: 选用SPF 级雌性SD 大鼠共40 只 …

Chitosan decorated oleosomes loaded propranolol hydrochloride hydrogel repurposed for Candida albicans-vaginal infection

MA Eltabeeb, MM Abdellatif, MA El-Nabarawi… - …, 2024 - Taylor & Francis
Aim: Our investigation aims to estimate the antifungal effect of propranolol hydrochloride
(PNL). Methods: Oleosomes (OLs) were fabricated by thin-film hydration and evaluated for …