Osteogenic differentiation cues of the bone morphogenetic protein-9 (BMP-9) and its recent advances in bone tissue regeneration

A Bharadwaz, AC Jayasuriya - Materials science and engineering: C, 2021 - Elsevier
Bone regeneration using bioactive molecules and biocompatible materials is growing
steadily with the advent of the new findings in cellular signaling. Bone Morphogenetic …

Targeted delivery as key for the success of small osteoinductive molecules

ER Balmayor - Advanced drug delivery reviews, 2015 - Elsevier
Molecules such as growth factors, peptides and small molecules can guide cellular behavior
and are thus important for tissue engineering. They are rapidly emerging as promising …

Coating of biomaterial scaffolds with the collagen-mimetic peptide GFOGER for bone defect repair

AM Wojtowicz, A Shekaran, ME Oest, KM Dupont… - Biomaterials, 2010 - Elsevier
Healing large bone defects and non-unions remains a significant clinical problem. Current
treatments, consisting of auto and allografts, are limited by donor supply and morbidity …

Murine preosteoblast differentiation induced by a peptide derived from bone morphogenetic proteins-9

E Bergeron, H Senta, A Mailloux, H Park… - … Engineering Part A, 2009 - liebertpub.com
Bone morphogenetic proteins (BMPs) increase the differentiation of osteoblasts implicated
in bone formation and repair. In a previous study, we demonstrated that a peptide derived …

Peptide‐modified bone repair materials: Factors influencing osteogenic activity

J Liao, S Wu, K Li, Y Fan, N Dunne… - Journal of Biomedical …, 2019 - Wiley Online Library
Many factors have been demonstrated as having an influencing effect on the osteogenic
activity of the peptide‐modified bone repair materials. However, most of studies only focus …

Modulation of MAPK signalling by immobilized adhesive peptides: Effect on stem cell response to BMP-9-derived peptides

S Beauvais, O Drevelle, MA Lauzon, A Daviau… - Acta biomaterialia, 2016 - Elsevier
Biomimetic materials were developed to regulate stem cell behaviour. We have analyzed
the influence of polycaprolactone (PCL) films, functionalized with adhesive peptides derived …

Effect of functionalized polycaprolactone on the behaviour of murine preosteoblasts

O Drevelle, E Bergeron, H Senta, MA Lauzon, S Roux… - Biomaterials, 2010 - Elsevier
The efficiency of biomaterials used in bone repair depends greatly on their ability to interact
with bone cells. Hence, we have functionalized polycaprolactone (PCL) films by peptides …

Cellular responses of histatin-derived peptides immobilized titanium surface using a tresyl chloride-activated method

P Siwakul, L Sirinnaphakorn, J Suwanprateep… - Dental Materials …, 2021 - jstage.jst.go.jp
Effects of histatin-derived peptides immobilization by tresyl chloride-activation technique for
MC3T3-E1 cellular responses on titanium (Ti) were evaluated. MC3T3-E1 were cultured on …

Adhesion, intracellular signalling and osteogenic differentiation of mesenchymal progenitor cells and preosteoblasts on poly (epsilon) caprolactone films …

J Jann, O Drevelle, MA Lauzon, N Faucheux - Materials Science and …, 2020 - Elsevier
Biomaterials that can control the behaviour of stem cells play a major role in regenerative
medicine and tissue engineering. We previously showed that poly (epsilon) caprolactone …

Controlled spatial and conformational display of immobilised bone morphogenetic protein-2 and osteopontin signalling motifs regulates osteoblast adhesion and …

EA Mitchell, BT Chaffey, AW McCaskie, JH Lakey… - BMC biology, 2010 - Springer
Background The interfacial molecular mechanisms that regulate mammalian cell growth and
differentiation have important implications for biotechnology (production of cells and cell …