Deciphering cell–cell interactions and communication from gene expression

E Armingol, A Officer, O Harismendy… - Nature Reviews …, 2021 - nature.com
Cell–cell interactions orchestrate organismal development, homeostasis and single-cell
functions. When cells do not properly interact or improperly decode molecular messages …

Machine learning for clinical decision support in infectious diseases: a narrative review of current applications

N Peiffer-Smadja, TM Rawson, R Ahmad… - Clinical Microbiology …, 2020 - Elsevier
Background Machine learning (ML) is a growing field in medicine. This narrative review
describes the current body of literature on ML for clinical decision support in infectious …

Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Strategies for new and improved vaccines against ticks and tick‐borne diseases

J de la Fuente, P Kopáček, A Lew‐Tabor… - Parasite …, 2016 - Wiley Online Library
Ticks infest a variety of animal species and transmit pathogens causing disease in both
humans and animals worldwide. Tick–host–pathogen interactions have evolved through …

Pathogen effectors: exploiting the promiscuity of plant signaling hubs

E Ceulemans, HMM Ibrahim, B De Coninck… - Trends in Plant …, 2021 - cell.com
Pathogens produce effectors to overcome plant immunity, thereby threatening crop yields
and global food security. Large-scale interactomic studies have revealed that pathogens …

DeNovo: virus-host sequence-based protein–protein interaction prediction

FE Eid, M ElHefnawi, LS Heath - Bioinformatics, 2016 - academic.oup.com
Motivation Can we predict protein–protein interactions (PPIs) of a novel virus with its host?
Three major problems arise: the lack of known PPIs for that virus to learn from, the cost of …

Protein interaction networks: centrality, modularity, dynamics, and applications

X Meng, W Li, X Peng, Y Li, M Li - Frontiers of Computer Science, 2021 - Springer
In the post-genomic era, proteomics has achieved significant theoretical and practical
advances with the development of high-throughput technologies. Especially the rapid …

[HTML][HTML] Artificial intelligence approaches to human-microbiome protein–protein interactions

H Lim, F Cankara, CJ Tsai, O Keskin… - Current Opinion in …, 2022 - Elsevier
Host-microbiome interactions play significant roles in human health and disease. Artificial
intelligence approaches have been developed to better understand and predict the …

Machine learning and its applications for protozoal pathogens and protozoal infectious diseases

RS Hu, AEL Hesham, Q Zou - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
In recent years, massive attention has been attracted to the development and application of
machine learning (ML) in the field of infectious diseases, not only serving as a catalyst for …

Structural host-microbiota interaction networks

E Guven-Maiorov, CJ Tsai… - PLoS computational …, 2017 - journals.plos.org
Hundreds of different species colonize multicellular organisms making them
“metaorganisms”. A growing body of data supports the role of microbiota in health and in …