One of the current stumbling blocks in our fight against cancer is the development of
acquired resistance to therapy, which is attributable to approximately 90% of cancer-related …

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of pathologically
activated, mostly immature, myeloid cells that exert robust immunosuppressive functions …

Our previous studies have showed that CC motif chemokine ligand 20 (CCL20) advanced
tumor progression and enhanced the chemoresistance of cancer cells by positively …

Solid tumors can be divided into benign solid tumors and solid malignant tumors in the
academic community, among which malignant solid tumors are called cancers. Cancer is …

The Cu 2+ complex formed by the coordination of disulfiram (DSF) metabolite
diethyldithiocarbamate (DTC), Cu (DTC) 2, can effectively inhibit tumor growth. However …

Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …

Tumors are intricate ecosystems containing malignant components that generate adaptive
and evolutionarily driven abnormal tissues. Through self-renewal and differentiation …

Background Mitochondrial dynamics play a fundamental role in determining stem cell fate.
However, the underlying mechanisms of mitochondrial dynamics in the stemness acquisition …

Aldehyde dehydrogenases 1 family member A1 (ALDH1A1) gene codes a cytoplasmic
enzyme and shows vital physiological and pathophysiological functions in many areas …

Cancer stem cells (CSCs) cause tumor metastasis and immune evasion by as-yet-unknown
molecular mechanisms. In the present study, we identify a long noncoding RNA (lncRNA) …