Hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions

M Kadem, L Garber, M Abdelkhalek… - IEEE Reviews in …, 2022 - ieeexplore.ieee.org
Cardiovascular disease is a deadly global health crisis that carries a substantial financial
burden. Innovative treatment and management of cardiovascular disease straddles …

Virtual (computed) fractional flow reserve: future role in acute coronary syndromes

HA Haley, M Ghobrial, PD Morris, R Gosling… - Frontiers in …, 2021 - frontiersin.org
The current management of acute coronary syndromes (ACS) is with an invasive strategy to
guide treatment. However, identifying the lesions which are physiologically significant can …

Prognostic value of postpercutaneous coronary intervention Murray-law-based quantitative flow ratio: post hoc analysis from FLAVOUR Trial

D Ding, J Zhang, P Wu, Z Wang, H Shi, W Yu, X Hu… - JACC: Asia, 2025 - jacc.org
Background Coronary physiology measured by fractional flow reserve (FFR) is superior to
angiography for assessing the efficacy of percutaneous coronary intervention (PCI). Yet, the …

Diagnostic accuracy of coronary angiography-based vessel fractional flow reserve (vFFR) virtual stenting

M Tomaniak, T Neleman… - Journal of Clinical …, 2022 - mdpi.com
3D coronary angiography-based vessel fractional flow reserve (vFFR) proved to be an
accurate diagnostic alternative to invasively measured pressure wire based fractional flow …

Assessment of the functional severity of coronary lesions from optical coherence tomography based on ensembled learning

IA Tache, CA Hatfaludi, A Puiu, LM Itu… - BioMedical Engineering …, 2023 - Springer
Background Atherosclerosis is one of the most frequent cardiovascular diseases. The
dilemma faced by physicians is whether to treat or postpone the revascularization of lesions …

Impact of intracoronary assessments on revascularization decisions: A contemporary evaluation

T Gillmore, RG Jung, R Moreland… - Catheterization and …, 2022 - Wiley Online Library
Objectives To investigate the real‐world implementation of intracoronary assessment (ICA)
techniques and evaluate their impact on clinical decisions regarding the management of …

Modelled impact of virtual fractional flow reserve in patients undergoing coronary angiography (VIRTU-4)

M Ghobrial, H Haley, R Gosling, DJ Taylor… - Heart, 2024 - heart.bmj.com
Background The practical application of 'virtual'(computed) fractional flow reserve (vFFR)
based on invasive coronary angiogram (ICA) images is unknown. The objective of this …

Quantitative flow ratio and virtual percutaneous coronary intervention for serial coronary stenoses: attractive technology, but still crawling

W Sumaya, MA Mamas, R Bagur - Journal of the American Heart …, 2022 - Am Heart Assoc
Coronary physiology assessment is an important field in which emerging technologies have
been successfully used in facilitating decision-making in interventional cardiology. This …

[PDF][PDF] Novel computational functional assessment of coronary

D Ding - Methodology, 2023 - core.ac.uk
Coronary angiography has limited efficacy in identifying patients with suboptimal results
after percutaneous coronary intervention (PCI). Immediate post-procedural functional …

[PDF][PDF] How Will Virtual (Computed) Fractional Flow Reserve (FFR) Impact the Management of Patients with Chronic Coronary Syndromes? The VIRTU-4 CCS Trial

M Ghobrial - 2021 - etheses.whiterose.ac.uk
Background Fractional flow reserve is the 'gold-standard'method for the measurement of
coronary artery stenosis physiological significance. FFR-guided revascularisation has a …