Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …

Since the discovery of a specific autoantibody in patients with neuromyelitis optica spectrum
disorder (NMOSD) in 2004, the water channel aquaporin-4 (AQP4) has attracted attention as …

Edema formation following traumatic spinal cord injury (SCI) exacerbates secondary injury,
and the severity of edema correlates with worse neurological outcome in human patients. To …

The neurovascular unit (NVU) consists of cells intrinsic to the vessel wall, the endothelial
cells and pericytes, and astrocyte endfeet that surround the vessel but are separated from it …

The cells of the choroid plexus (CP) epithelium are specialized ependymal cells (ECs) but
have distinct properties. The CP cells and ECs form single‐cell sheets contiguous to each …

The choroid plexus (CP) consists of specialized ependymal cells and underlying blood
vessels and stroma producing the bulk of the cerebrospinal fluid (CSF). CP epithelial cells …

Aquaporins (AQPs) are ubiquitous channel proteins that play a critical role in the
homeostasis of the cellular environment by allowing the transit of water, chemicals, and ions …

AQP4-IgG is an autoantibody associated with neuromyelitis optica spectroscopic disorder
(NMOSD), a central nervous system inflammatory disease that requires early diagnosis and …

Background Rho-kinase inhibition in a rat middle cerebral artery occlusion (MCAO) model is
reported to improve neurological functions and decrease infarction size. Objective The …

Pathological pain presents significant challenges in clinical practice and research.
Aquaporin-4 (AQP4), which is primarily found in astrocytes, is being considered as a …