Neurotransmitters and neuromodulators have a wide range of key roles throughout the
nervous system. However, their dynamics in both health and disease have been challenging …

Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Estimating the pose of multiple animals is a challenging computer vision problem: frequent
interactions cause occlusions and complicate the association of detected keypoints to the …

We developed a miniaturized two-photon microscope (MINI2P) for fast, high-resolution,
multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a …

Tethered and battery-powered devices that interface with neural tissues can restrict natural
motions and prevent social interactions in animal models, thereby limiting the utility of these …

Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by
environmental influences, and functionally implicated in behavioural responses to stress …

Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …

Deciding when and whether to move is critical for survival. Loss of dopamine neurons
(DANs) of the substantia nigra pars compacta (SNc) in patients with Parkinson's disease …

Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

Interest in deciphering the fundamental mechanisms and processes of the human mind
represents a central driving force in modern neuroscience research. Activities in support of …