Molecular evolution of human coronavirus genomes
Human coronaviruses (HCoVs), including SARS-CoV and MERS-CoV, are zoonotic
pathogens that originated in wild animals. HCoVs have large genomes that encode a fixed …
pathogens that originated in wild animals. HCoVs have large genomes that encode a fixed …
Recombination in viruses: mechanisms, methods of study, and evolutionary consequences
Recombination is a pervasive process generating diversity in most viruses. It joins variants
that arise independently within the same molecule, creating new opportunities for viruses to …
that arise independently within the same molecule, creating new opportunities for viruses to …
Bat coronaviruses related to SARS-CoV-2 and infectious for human cells
S Temmam, K Vongphayloth, E Baquero, S Munier… - Nature, 2022 - nature.com
The animal reservoir of SARS-CoV-2 is unknown despite reports of SARS-CoV-2-related
viruses in Asian Rhinolophus bats,,–, including the closest virus from R. affinis, RaTG13 …
viruses in Asian Rhinolophus bats,,–, including the closest virus from R. affinis, RaTG13 …
Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission
Wildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral
variants that can emerge to infect humans. In North America, there is phylogenomic …
variants that can emerge to infect humans. In North America, there is phylogenomic …
Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic
There are outstanding evolutionary questions on the recent emergence of human
coronavirus SARS-CoV-2 including the role of reservoir species, the role of recombination …
coronavirus SARS-CoV-2 including the role of reservoir species, the role of recombination …
[HTML][HTML] ACE2 binding is an ancestral and evolvable trait of sarbecoviruses
Two different sarbecoviruses have caused major human outbreaks in the past two decades,.
Both of these sarbecoviruses, SARS-CoV-1 and SARS-CoV-2, engage ACE2 through the …
Both of these sarbecoviruses, SARS-CoV-1 and SARS-CoV-2, engage ACE2 through the …
HyPhy 2.5—a customizable platform for evolutionary hypothesis testing using phylogenies
SL Kosakovsky Pond, AFY Poon… - Molecular biology …, 2020 - academic.oup.com
Abstract HYpothesis testing using PHYlogenies (HyPhy) is a scriptable, open-source
package for fitting a broad range of evolutionary models to multiple sequence alignments …
package for fitting a broad range of evolutionary models to multiple sequence alignments …
Datamonkey 2.0: a modern web application for characterizing selective and other evolutionary processes
Inference of how evolutionary forces have shaped extant genetic diversity is a cornerstone of
modern comparative sequence analysis. Advances in sequence generation and increased …
modern comparative sequence analysis. Advances in sequence generation and increased …
Persistent HIV-1 replication maintains the tissue reservoir during therapy
Lymphoid tissue is a key reservoir established by HIV-1 during acute infection. It is a site
associated with viral production, storage of viral particles in immune complexes, and viral …
associated with viral production, storage of viral particles in immune complexes, and viral …
PLS-based model selection: The role of alternative explanations in information systems research
Exploring theoretically plausible alternative models for explaining the phenomenon under
study is a crucial step in advancing scientific knowledge. This paper advocates model …
study is a crucial step in advancing scientific knowledge. This paper advocates model …