Spirocyclic β-lactams: synthesis and biological evaluation of novel heterocycles

SS Bari, A Bhalla - Heterocyclic Scaffolds I: ß-Lactams, 2010 - Springer
Abstract β-Lactam rings containing compounds are a group of antibiotics of unparalleled
importance in chemotherapy. Considerable effort has been reported in the development of …

General, mild, and metal-free synthesis of phenyl selenoesters from anhydrides and their use in peptide synthesis

A Temperini, F Piazzolla, L Minuti… - The Journal of …, 2017 - ACS Publications
A mild, practical, and simple procedure for phenyl selenoesters synthesis from several
anhydrides and diphenyl diselenide was developed. This transition-metal-free method …

Synthesis of sugar-derived isoselenocyanates, selenoureas, and selenazoles

O Lopez, S Maza, V Ulgar, I Maya… - Tetrahedron, 2009 - Elsevier
Aryl, alkyl, and sugar-derived isoselenocyanates were prepared by a one-pot procedure
starting from the corresponding formamides, using triphosgene as a dehydrating agent …

Novel peptidomimetic compounds containing redox active chalcogens and quinones as potential anticancer agents

S Shaaban, R Diestel, B Hinkelmann… - European journal of …, 2012 - Elsevier
Many types of cancer cells are associated with a disturbed intracellular redox balance and
oxidative stress (OS). Among the various agents employed to modulate the intracellular …

Organoselenium compounds. Synthesis, application, and biological activity

R Ferdousian, FK Behbahani - … , Sulfur, and Silicon and the Related …, 2022 - Taylor & Francis
We review green solvent alternatives in organoselenium chemistry. We present the
application of ionic liquids and deep eutectic solvents for the synthesis of seleno …

Facile synthesis of novel halogenated 4-pyrazolylspirocyclic-β-lactams: versatile heterocyclic synthons

A Bhalla, SS Bari, J Bhalla, S Khullar, S Mandal - Tetrahedron Letters, 2016 - Elsevier
A mild approach for the synthesis of halogenated 4-pyrazolylspirocyclic-β-lactams via
halogen (I 2, Br 2, ICl) mediated intrasulfenyl cyclisation of cis-3-(prop-2′-ynyloxy)-4 …

Simple cleavage of diorganyl diselenides with NaBH4/PEG-400 and direct Michael addition to electron-deficient alkenes

G Perin, EL Borges, PC Rosa, PN Carvalho… - Tetrahedron …, 2013 - Elsevier
Nucleophilic species of selenium were generated in situ from the reaction of diorganyl
diselenide with NaBH4 in PEG-400 as solvent and selectively added to several α, β …

Seleno-β-lactams: synthesis of monocyclic and spirocyclic selenoazetidin-2-ones

A Bhalla, P Venugopalan, KK Bhasin, SS Bari - Tetrahedron, 2007 - Elsevier
An efficient protocol for the synthesis of novel seleno-β-lactams using operationally simple
strategies is presented. 3-Phenyl/benzylseleno-β-lactams, obtained from 2-phenyl …

A simple zinc-mediated method for selenium addition to Michael acceptors

FG Nacca, B Monti, EJ Lenardão, P Evans, C Santi - Molecules, 2020 - mdpi.com
In this work, we focused our attention on seleno-Michael type reactions. These were
performed using zinc-selenolates generated in situ from diphenyl diselenide 1, 1, 2-bis (3 …

Serendipitous discovery of a regioselective synthesis of novel benzoyloxy substituted phenyl/benzyl-sulfanyl/selenylbisesters, 3-benzoyloxy-3-(phenylsulfanyl)-β …

D Narula, SS Bari, G Singh, R Sharma… - Journal of Sulfur …, 2023 - Taylor & Francis
The regioselective benzoyloxylation process involves stirring a mixture of phenyl/benzyl-
sulfanyl/selenylethanoate 1a-c with appropriate oxidant [benzoyl peroxide (BPO) 2a/m …