Introduction Schiff bases are compounds with characteristic features of azomethine linkage (-
C= N-). Schiff bases are capable of coordinating with metal ions via azomethine nitrogen …

1, 2, 4-Oxadiazole is an essential motif in drug discovery represented in many experimental,
investigational, and marketed drugs. This review covers synthetic methods that allow the …

The c-MYC oncogene regulates multiple cellular activities and is a potent driver of many
highly aggressive human cancers, such as leukemia and triple-negative breast cancer. The …

The aim of the current work is to synthesize some new 1, 3, 4-oxadiazole derivatives bearing
3, 4-dihydroxyphenyl acetic acid scaffold as a novel class of α-glucosidase inhibitors. A …

Thirty oxadiazole derivatives 1–30 were synthesized via nucleophilic substitution reactions
between 1, 3, 4-oxadiazole-2-thiol and benzyl/phenacyl halides. The structural elucidation of …

A series of novel 1, 3, 4-oxadiazole-artemisinin hybrids have been designed and
synthesized. An MTT assay revealed that most of tested hybrids showed more enhanced …

A pivotal feature of present research study is the synthesis of some new 2, 5‐bis (pyrazolyl)‐
1, 3, 4‐oxadiazoles as promising α‐glucosidase inhibitors. In this regard, a facile reaction …

The report from the WHO, there are 2 million deaths in worldwide due to cancer in the year
2023. Due to increase death rate, the researchers need to find a new drug for targeting …

The thiadiazole-pyrazole hybrid 3 was synthesized by treating 2-cyano-3, 3-bis (methylthio)-
N-(5-phenyl-1, 3, 4-thiadiazol-2-yl) acrylamide (2) with hydrazine hydrate, and employed in …

The new novel Oxadiazole derivatives linked to Indole moiety were prepared, and biological
screened for the anti-microbial activities. These compounds (3) and (4) were obtained from …