Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …

Metabolic rewiring is considered as a primary feature of cancer. Malignant cells reprogram
metabolism pathway in response to various intrinsic and extrinsic drawback to fuel cell …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …

Glycosphingolipids (GSL s) comprise a heterogeneous group of membrane lipids formed by
a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans …

Hepatitis C virus (HCV) leads to progressive liver disease and hepatocellular carcinoma.
Current treatments are only partially effective, and new therapies targeting viral and host …

Lipids play a diverse and critical role in cellular processes in all tissues. The unique lipid
composition of nerve membranes is particularly interesting because it contains, among other …

Gangliosides, the glycosphingolipids carrying one or several sialic acid residues, are
located on the outer leaflet of the plasma membrane in glycolipid-enriched microdomains …

At the plasma membrane, gangliosides, a group of glycosphingolipids, are expressed along
with glycosphingolipids, phospholipids, and cholesterol in so-called lipid rafts that interact …