Francisella tularensis is a tier 1 select agent responsible for tularemia in humans and a wide
variety of animal species. Extensive research into understanding the virulence factors of the …

Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a
severe disease called tularemia. It secretes unusually shaped nanotubular outer membrane …

The notoriety of high-consequence human pathogens has increased in recent years and,
rightfully, research efforts have focused on understanding host-pathogen interactions …

Release of outer membrane vesicles (OMV) is an important phenomenon in Gram-negative
bacteria playing multiple roles in their lifestyle, including in relation to virulence and host …

Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the
northern hemisphere. F. tularensis has long been developed as a biological weapon due to …

Biofilms have been established as an important lifestyle for bacteria in nature as these
structured communities often enable survivability and persistence in a multitude of …

Low-molecular weight (LMW) thiols, encompassing peptides and small proteins with active
cysteine residue (s), are important to bacteria as they are involved in a wide range of redox …

Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by
the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of …

Francisella tularensis is the etiologic agent of tularemia, and subspecies tularensis (type A)
is the most virulent subspecies. The live vaccine strain (LVS) of subspecies holarctica …

Two clinically important subspecies, Francisella tularensis subsp. tularensis (type A) and F.
tularensis subsp. holarctica (type B) are responsible for most tularaemia cases, but these …