Most of the cytotoxic chemotherapeutic agents have poor aqueous solubility. These
molecules are associated with poor physicochemical and biopharmaceutical properties …

Protein-based nanocarriers have gained considerable attention as colloidal carrier systems
for the delivery of anticancer drugs. Protein nanocarriers possess various advantages …

Diosmin (DSN) is an outstanding phlebotonic flavonoid with a tolerable potential for the
treatment of colon and hepatocellular carcinoma. Being highly insoluble, DSN bioavailability …

The real problem in pharmaceutical preparation is drugs' poor aqueous solubility, low
permeability through biological membranes, and short biological t1/2. Conventional drug …

Propylene glycol (PG)-phospholipid vesicles have been advocated as flexible lipid vesicles
for enhanced skin delivery of drugs. To further characterize the performance of these …

Lung cancer and pandemic acute respiratory disease, COVID-19, are examples of the most
worldwide widespread diseases. The aim of the current study is to develop cyclodextrin …

This work reviews the examples of the application of lyophilization and its cryogenic
modifications as the production method of solid dispersions and drug nanocrystals, two …

The current study was aimed to develop an amphiphilic drug-lipid nano-complex of rutin:
egg phosphatidylcholine (EPC) to enhance its poor absorption and bioavailability, and …

An innovative, rapid and simple electrochemical approach for the reliable quantification of
cytostatic drug flutamide (FLU) in various matrices is herein proposed. This platform involves …

A novel particulate delivery matrix based on ionically crosslinked casein (CAS)
nanoparticles was developed for controlled release of the poorly soluble anticancer drug …