Acoustofluidic micromixers: From rational design to lab-on-a-chip applications

Z Chen, L Shen, X Zhao, H Chen, Y Xiao, Y Zhang… - Applied Materials …, 2022 - Elsevier
Microfluidics that permits to manipulate fluids at the micrometer or submicrometer scale
offers fundamentally new opportunities in chemical and biomedical engineering. The past …

Ultrasound-responsive systems as components for smart materials

AG Athanassiadis, Z Ma, N Moreno-Gomez… - Chemical …, 2021 - ACS Publications
Smart materials can respond to stimuli and adapt their responses based on external cues
from their environments. Such behavior requires a way to transport energy efficiently and …

Investigation of acoustic streaming patterns around oscillating sharp edges

N Nama, PH Huang, TJ Huang, F Costanzo - Lab on a Chip, 2014 - pubs.rsc.org
Oscillating sharp edges have been employed to achieve rapid and homogeneous mixing in
microchannels using acoustic streaming. Here, we used a perturbation approach to study …

Amplification of acoustic forces using microbubble arrays enables manipulation of centimeter-scale objects

R Goyal, AG Athanassiadis, Z Ma, P Fischer - Physical review letters, 2022 - APS
Manipulation of macroscale objects by sound is fundamentally limited by the wavelength
and object size. Resonant subwavelength scatterers such as bubbles can decouple these …

Versatile acoustic manipulation of micro-objects using mode-switchable oscillating bubbles: transportation, trapping, rotation, and revolution

W Zhang, B Song, X Bai, L Jia, L Song, J Guo, L Feng - Lab on a Chip, 2021 - pubs.rsc.org
Controllable on-chip multimodal manipulation of micro-objects in microfluidic devices is
urgently required for enhancing the efficiency of potential biomedical applications. However …

Multiplexed detection of cancer biomarkers using a microfluidic platform integrating single bead trapping and acoustic mixing techniques

H Chen, C Chen, S Bai, Y Gao, G Metcalfe, W Cheng… - Nanoscale, 2018 - pubs.rsc.org
It is critical to reliably and rapidly detect multiple disease biomarkers in tiny liquid samples
with high sensitivity to meet the growing demand for point-of-care diagnostics. This paper …

Versatile hybrid acoustic micromixer with demonstration of circulating cell-free DNA extraction from sub-ml plasma samples

AJ Conde, I Keraite, AE Ongaro, M Kersaudy-Kerhoas - Lab on a Chip, 2020 - pubs.rsc.org
Acoustic micromixers have attracted considerable attention in the last years since they can
deliver high mixing efficiencies without the need for movable components. However, their …

Probing cell deformability via acoustically actuated bubbles

Y Xie, N Nama, P Li, Z Mao, PH Huang, C Zhao… - Small, 2016 - Wiley Online Library
An acoustically actuated, bubble‐based technique is developed to investigate the
deformability of cells suspended in microfluidic devices. A microsized bubble is generated …

On-chip simultaneous rotation of large-scale cells by acoustically oscillating bubble array

Q Tang, F Liang, L Huang, P Zhao, W Wang - Biomedical Microdevices, 2020 - Springer
Bubbles locating in microfluidic chamber can produce acoustic streaming vortices by
applying travelling surface acoustic wave oscillation in an ultrasonic range, which can be …

Study of ultrasound thrombolysis using acoustic bubbles in a microfluidic device

Y Gao, M Wu, BI Gaynes, RS Dieter, J Xu - Lab on a Chip, 2021 - pubs.rsc.org
Thrombosis is a common medical entity associated with many forms of cardiovascular
disease including myocardial infarction and stroke. Recently, ultrasound thrombolysis has …