Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity
S Fujii, S Yamasaki, T Iyoda, K Shimizu - Inflammation and Regeneration, 2022 - Springer
Coronaviruses regularly cause outbreaks of zoonotic diseases characterized by severe
pneumonia. The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS …
pneumonia. The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS …
Comparison of antibody and T cell responses elicited by BBIBP-CorV (Sinopharm) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 in healthy adult …
I Vályi-Nagy, Z Matula, M Gönczi, S Tasnády, G Bekő… - Geroscience, 2021 - Springer
In the present study, humoral and T cell-mediated immune responses elicited by BBIBP-
CorV (inactivated virus) and BNT162b2 (mRNA-based) vaccines against SARS-CoV-2 virus …
CorV (inactivated virus) and BNT162b2 (mRNA-based) vaccines against SARS-CoV-2 virus …
A complementary union of SARS-CoV2 natural and vaccine induced immune responses
J Torresi, MA Edeling, T Nolan, DI Godfrey - Frontiers in Immunology, 2022 - frontiersin.org
Our understanding of the immune responses that follow SARS-CoV-2 infection and
vaccination has progressed considerably since the COVID-19 pandemic was first declared …
vaccination has progressed considerably since the COVID-19 pandemic was first declared …
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status
While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to
determine how booster doses and prior infection influence the immune defense they elicit …
determine how booster doses and prior infection influence the immune defense they elicit …
Dominant CD8+ T Cell Nucleocapsid Targeting in SARS-CoV-2 Infection and Broad Spike Targeting From Vaccination
E Taus, C Hofmann, FJ Ibarrondo, MA Hausner… - Frontiers in …, 2022 - frontiersin.org
CD8+ T cells have key protective roles in many viral infections. While an overall Th1-biased
cellular immune response against SARS-CoV-2 has been demonstrated, most reports of anti …
cellular immune response against SARS-CoV-2 has been demonstrated, most reports of anti …
Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model
A Patel, JN Walters, EL Reuschel, K Schultheis… - Cell Reports …, 2021 - cell.com
Summary Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has
had a dramatic global impact on public health and social and economic infrastructures …
had a dramatic global impact on public health and social and economic infrastructures …
Deep phenotypic analysis of blood and lymphoid T and NK cells from HIV+ controllers and ART-suppressed individuals
AF George, X Luo, J Neidleman, R Hoh… - Frontiers in …, 2022 - frontiersin.org
T and natural killer (NK) cells are effector cells with key roles in anti-HIV immunity, including
in lymphoid tissues, the major site of HIV persistence. However, little is known about the …
in lymphoid tissues, the major site of HIV persistence. However, little is known about the …
Mild SARS-CoV-2 infection results in long-lasting microbiota instability
V Upadhyay, RK Suryawanshi, P Tasoff… - Mbio, 2023 - Am Soc Microbiol
Viruses targeting mammalian cells can indirectly alter the gut microbiota, potentially
compounding their phenotypic effects. Multiple studies have observed a disrupted gut …
compounding their phenotypic effects. Multiple studies have observed a disrupted gut …
CD4+ T cell immune specificity changes after vaccination in healthy and COVID-19 convalescent subjects
L Esparcia-Pinedo, P Martínez-Fleta, N Ropero… - Frontiers in …, 2022 - frontiersin.org
The immune response promoted by SARS-CoV-2 vaccination is relevant to develop novel
vaccines and optimized prevention strategies. We analyzed the adaptive immunity in healthy …
vaccines and optimized prevention strategies. We analyzed the adaptive immunity in healthy …