Selenium and selenoproteins in health

F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

Hydrogenases

W Lubitz, H Ogata, O Rudiger, E Reijerse - Chemical reviews, 2014 - ACS Publications
The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes

PP Chan, BY Lin, AJ Mak, TM Lowe - Nucleic acids research, 2021 - academic.oup.com
Abstract tRNAscan-SE has been widely used for transfer RNA (tRNA) gene prediction for
over twenty years, developed just as the first genomes were decoded. With the massive …

RefSeq: an update on prokaryotic genome annotation and curation

DH Haft, M DiCuccio, A Badretdin, V Brover… - Nucleic acids …, 2018 - academic.oup.com
Abstract The Reference Sequence (RefSeq) project at the National Center for Biotechnology
Information (NCBI) provides annotation for over 95 000 prokaryotic genomes that meet …

[HTML][HTML] Functions of elements in soil microorganisms

M Hemkemeyer, SA Schwalb, S Heinze… - Microbiological …, 2021 - Elsevier
The soil microbial community fulfils various functions, such as nutrient cycling and carbon
(C) sequestration, therefore contributing to maintenance of soil fertility and mitigation of …

Biomarkers of selenium status

GF Combs Jr - Nutrients, 2015 - mdpi.com
The essential trace element, selenium (Se), has multiple biological activities, which depend
on the level of Se intake. Relatively low Se intakes determine the expression of …

[HTML][HTML] [NiFe] hydrogenases: a common active site for hydrogen metabolism under diverse conditions

HS Shafaat, O Rüdiger, H Ogata, W Lubitz - Biochimica et Biophysica Acta …, 2013 - Elsevier
Hydrogenase proteins catalyze the reversible conversion of molecular hydrogen to protons
and electrons. The most abundant hydrogenases contain a [NiFe] active site; these proteins …

Natural expansion of the genetic code

A Ambrogelly, S Palioura, D Söll - Nature chemical biology, 2007 - nature.com
At the time of its discovery four decades ago, the genetic code was viewed as the result of a
“frozen accident.” Our current knowledge of the translation process and of the detailed …

Selenoproteins—what unique properties can arise with selenocysteine in place of cysteine?

ESJ Arnér - Experimental cell research, 2010 - Elsevier
The defining entity of a selenoprotein is the inclusion of at least one selenocysteine (Sec)
residue in its sequence. Sec, the 21st naturally occurring genetically encoded amino acid …

Composition and evolution of the vertebrate and mammalian selenoproteomes

M Mariotti, PG Ridge, Y Zhang, AV Lobanov… - PloS one, 2012 - journals.plos.org
Background Selenium is an essential trace element in mammals due to its presence in
proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing …