Insulin-secreting pancreatic β-cells play a critical role in blood glucose homeostasis and the
development of type 2 diabetes (T2D) in the context of insulin resistance. Based on data …

The enzyme catalase catalyzes the breakdown of hydrogen peroxide into oxygen and water.
It is the main regulator of hydrogen peroxide metabolism. Hydrogen peroxide is a highly …

Hydrogen peroxide is produced endogenously and can be toxic to living organisms by
inducing oxidative stress and cell damage. However, it has also been identified as a signal …

Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in the destruction of
insulin-secreting β cells of the islets of Langerhans. Allogeneic islet transplantation could be …

Macrophages have been demonstrated to suppress T cell responses by producing reactive
oxygen species (ROS) leading to the subsequent induction of T regulatory cells in a ROS …

Excessive glucocorticoid (GC) usage may lead to non-traumatic femoral head
osteonecrosis. Dexamethasone (Dex) exerts cytotoxic effect to cultured osteoblasts. Here …

Fluoride intoxication and dexamethasone treatment produce deleterious effects in bone and
brain. The aim of this study was to evaluate the effect of fluoride (F) and dexamethasone …

ABSTRACT PURPOSE: To evaluate metabolic effects in experimental model of
glucocorticoid-induced insulin resistance. METHODS: Twenty Wistar male rats were …

The aim of the present study was to investigate whether hydrocortisone induces oxidative
stress in hepatocytes and to evaluate the possible ameliorative effect of thymol against such …

Diabetes mellitus (DM) disrupts the pituitary-thyroid axis and leads to a higher prevalence of
thyroid disease. However, the role of reactive oxygen species in DM thyroid disease …