▪ Abstract The enteric nervous system exerts local control over mixing and propulsive
movements in the small intestine. When digestion is in progress, intrinsic primary afferent …

8.2. Effects in the pancreas 8.3. Effects on the intestinal sphincter 8.4. Effects on intestinal
motility 8.5. Effects on intestinal cellular proliferation 8.6. Effects on intestinal fluid and ion …

The preprotachykinin-A gene-derived peptides substance P and neurokinin (NK) A are
expressed in distinct neural pathways of the mammalian gut. When released from intrinsic …

The enteric nervous system (ENS) is comprised of a network of neurons and glial cells that
are responsible for coordinating many aspects of gastrointestinal function. These cells arise …

Previous studies have identified the chemistries, shapes, projections and
electrophysiological characteristics of several populations of neurons in the distal colon of …

Neuromedin U is a bioactive peptide first isolated from porcine spinal cord. In this paper, we
demonstrate that neuromedin U is the cognate ligand for the orphan G protein-coupled …

In recent decades, neuropeptides have been found to play a major role in communication
along the gut-brain axis. Various neuropeptides are expressed in the central and peripheral …

The architecture of the enteric nerve networks in the gastrointestinal tract appears to be
more complex in large mammals, including humans, than in small laboratory animals. At …

Modern research on gastrointestinal behavior has revealed it to be a highly complex
bidirectional process in which the gut sends signals to the brain, via spinal and vagal …

Gastrointestinal events such as peristalsis and secretion/absorption processes are
influenced by the enteric nervous system, which is capable of acting largely independently …