Endovascular management of acute stroke

TN Nguyen, M Abdalkader, U Fischer, Z Qiu, S Nagel… - The Lancet, 2024 - thelancet.com
Stroke related to large vessel occlusion is a leading cause of disability and death worldwide.
Advances in endovascular therapy to reopen occluded arteries have been shown to reduce …

Endovascular stroke thrombectomy for patients with large ischemic core: a review

H Chen, JS Lee, P Michel, B Yan… - JAMA neurology, 2024 - jamanetwork.com
Importance Recently, 6 randomized clinical trials—RESCUE-Japan-LIMIT (Recovery by
Endovascular Salvage for Cerebral Ultra-Acute Embolism—Japan Large Ischemic Core …

Hyperacute ischemic stroke care—Current treatment and future directions

BCV Campbell - International Journal of Stroke, 2024 - journals.sagepub.com
A decade on from the first positive thrombectomy trials, hyperacute therapies for ischemic
stroke continue to rapidly advance. Effective treatments remain limited to reperfusion …

Association of Mismatch Profiles and Clinical Outcome from Endovascular Therapy in Large Infarct: A Post‐Hoc Analysis of the ANGEL‐ASPECT Trial

X Huo, TN Nguyen, D Sun, Raynald, Y Pan… - Annals of …, 2024 - Wiley Online Library
Objectives We investigated whether patients with large infarct and the presence or absence
of perfusion mismatch are associated with endovascular treatment benefit. Methods This is a …

CLEAR thrombectomy score: an index to estimate the probability of good functional outcome with or without endovascular treatment in the late window for anterior …

JE Siegler, M Koneru, MM Qureshi… - Journal of the …, 2024 - ahajournals.org
Background With the expanding eligibility for endovascular therapy (EVT) of patients
presenting in the late window (6–24 hours after last known well), we aimed to derive a score …

Effect of hemoglobin and blood glucose levels on CT perfusion ischemic core estimation: a post hoc analysis of the ESCAPE-NA1 trial

U Pensato, S Bosshart, A Stebner, A Rohr, TJ Kleinig… - Neurology, 2024 - neurology.org
Background and Objectives CT perfusion (CTP) maps can estimate the ischemic core in
acute ischemic stroke based on distinctive cerebral blood flow thresholds. However …

Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4· 5 h of onset of ischaemic stroke (TASTE): a multicentre …

MW Parsons, V Yogendrakumar, L Churilov… - The Lancet …, 2024 - thelancet.com
Background Intravenous tenecteplase increases reperfusion in patients with salvageable
brain tissue on perfusion imaging and might have advantages over alteplase as a …

Expanding the Treatable Imaging Profile in Patients With Large Ischemic Stroke: Subanalysis From a Randomized Clinical Trial

M Inoue, T Yoshimoto, H Yamagami, K Toyoda… - Stroke, 2024 - Am Heart Assoc
BACKGROUND: We aimed to examine the boundary of the ischemic core volume in patients
undergoing endovascular thrombectomy (EVT) versus those receiving medical management …

Safety and clinical outcomes of endovascular therapy versus medical management in late presentation of large ischemic stroke

A Mujanovic, D Strbian, J Demeestere… - European stroke …, 2024 - journals.sagepub.com
Introduction: The benefit of endovascular therapy (EVT) among stroke patients with large
ischemic core (ASPECTS 0–5) in the extended time window outside of trial settings remains …

Stroke thrombectomy for large infarcts with limited penumbra: Systematic review and meta-analysis of randomized trials

H Chen, S Chaturvedi, D Gandhi… - American Journal of …, 2024 - ajnr.org
ABSTRACT BACKGROUND AND PURPOSE: Recent randomized trials have suggested that
endovascular thrombectomy (EVT) is superior to medical management (MM) for stroke …