Molecular and cellular mechanisms associated with effects of molecular hydrogen in cardiovascular and central nervous systems

M Barancik, B Kura, TW LeBaron, R Bolli, J Buday… - Antioxidants, 2020 - mdpi.com
The increased production of reactive oxygen species and oxidative stress are important
factors contributing to the development of diseases of the cardiovascular and central …

Nanomedicine‐based therapeutics for myocardial ischemic/reperfusion injury

X Li, W Ou, M Xie, J Yang, Q Li… - Advanced Healthcare …, 2023 - Wiley Online Library
Myocardial ischemic/reperfusion (IR) injury is a global cardiovascular disease with high
mortality and morbidity. Therapeutic interventions for myocardial ischemia involve restoring …

Berberine protects against simulated ischemia/reperfusion injury-induced H9C2 cardiomyocytes apoptosis in vitro and myocardial ischemia/reperfusion-induced …

N Zhu, J Li, Y Li, Y Zhang, Q Du, P Hao, J Li… - Frontiers in …, 2020 - frontiersin.org
Berberine (BBR) has a variety of pharmacological activities and is widely used in Asian
countries. However, the clinical application of BBR still lacks scientific basis, what protective …

Cardioprotective role of scopoletin on isoproterenol-induced myocardial infarction in rats

N Rong, R Yang, IAA Ibrahim, W Zhang - Applied Biochemistry and …, 2023 - Springer
Scopoletin is a phenolic coumarin isolated from a variety of plants and was originally used to
treat various diseases including arthritis as well as bone-related diseases. The goal of this …

Narrative on hydrogen therapy and its clinical applications: safety and efficacy

A Ahmad, AA Baig, M Hussain… - Current …, 2022 - benthamdirect.com
Molecular hydrogen proved itself as a novel therapeutic candidate and has been thriving
from the beginning with its potential clinical significance, higher affinity, and cellular integrity …

[HTML][HTML] Anti-inflammatory and anti-oxidative effects of myrtenol in the rats with allergic asthma

MA Rajizadeh, H Najafipour, MS Fekr… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
The aim of the present study was to investigate the effect of Myrtenol, the active ingredient of
Myrtle on the oxidant and anti-oxidant indices and cytokines in the allergic asthma. Allergic …

[HTML][HTML] S-limonene protects the heart in an experimental model of myocardial infarction induced by isoproterenol: Possible involvement of mitochondrial reactive …

P Rhana, GM Barros, VC de Oliveira Santos… - European Journal of …, 2022 - Elsevier
Background Myocardial infarction (MI) is associated with high mortality rates, despite the fact
that there are therapies available. Importantly, excessive oxidative stress may contribute to …

Naringin improves post-ischemic myocardial injury by activation of KATP channels

AM de Araujo, SVS de Cerqueira… - European Journal of …, 2023 - Elsevier
Naringin (NRG) is a flavonoid with recognized cardioprotective effects. Then, it was
investigated the cardioprotective mechanisms of NRG against ischemia-reperfusion (I/R) …

Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway

J Zhang, Y Wang, C Bao, T Liu… - International …, 2019 - spandidos-publications.com
Curcumin (CUR) has the ability to attenuate oxidative stress in the myocardium and to
protect the myocardium from lipotoxic injury owing to its lipid‑reducing properties. However …

d-Limonene Ameliorates Myocardial Infarction Injury by Reducing Reactive Oxygen Species and Cell Apoptosis in a Murine Model

AO Durco, DS de Souza, L Heimfarth… - Journal of natural …, 2019 - ACS Publications
Myocardial infarction (MI) leads to high mortality, and pharmacological or percutaneous
primary interventions do not significantly inhibit ischemia/reperfusion injuries, particularly …