Using whole-exome sequencing to examine the genetic causes of immune deficiency in 235
common variable immunodeficiency (CVID) patients seen in the United States (Mount Sinai …

The neonatal fragment crystallizable (Fc) receptor (FcRn) functions as a recycling
mechanism to prevent degradation and extend the half-life of IgG and albumin in the …

Background Diagnostic delay in common variable immunodeficiency disorders (CVID) is
considerable. There is no generally accepted symptom-recognition framework for its early …

Common variable immunodeficiency disorders (CVIDs) are the most frequent symptomatic
primary immune deficiencies (PIDs) in adults. Most patients suffer recurrent infections as a …

Activated PI3Kδ syndrome (APDS) is a rare inborn error of immunity (IEI) characterized
primarily by frequent infections, lymphoproliferation and autoimmunity. Since its initial …

Common variable immunodeficiency disorders (CVID) are the most frequent symptomatic
primary immune deficiency in adults. At this time, the causes of these conditions are …

Background Common variable immunodeficiency (CVID) is the most prevalent symptomatic
primary immunodeficiency disorder characterized by infectious and noninfectious …

Common variable immune deficiency (CVID) is one of the most common congenital immune
defects encountered in clinical practice. The condition occurs equally in males and females …

Immune responses to coronavirus disease 2019 (COVID-19) mRNA vaccines in primary
antibody deficiencies (PADs) are largely unknown. We investigated antibody and CD4+ T …

Abstract Background Serum immunoglobulin G (IgG) concentrations are integral to the
workup of immune deficiencies and IgG4-related disease (IgG4-RD). Demographic …