Critical assessment of methods of protein structure prediction (CASP)—Round XIII

A Kryshtafovych, T Schwede, M Topf… - Proteins: Structure …, 2019 - Wiley Online Library
CASP (critical assessment of structure prediction) assesses the state of the art in modeling
protein structure from amino acid sequence. The most recent experiment (CASP13 held in …

On the structural diversity and individuality of polymorphic amyloid protein assemblies

L Lutter, LD Aubrey, WF Xue - Journal of Molecular Biology, 2021 - Elsevier
The prediction of highly ordered three-dimensional structures of amyloid protein fibrils from
the amino acid sequences of their monomeric self-assembly precursors constitutes a …

Enhancing alphafold-multimer-based protein complex structure prediction with MULTICOM in CASP15

J Liu, Z Guo, T Wu, RS Roy, F Quadir, C Chen… - Communications …, 2023 - nature.com
Abstract To enhance the AlphaFold-Multimer-based protein complex structure prediction, we
developed a quaternary structure prediction system (MULTICOM) to improve the input fed to …

The impact of AI‐based modeling on the accuracy of protein assembly prediction: Insights from CASP15

B Ozden, A Kryshtafovych… - … : Structure, Function, and …, 2023 - Wiley Online Library
In CASP15, 87 predictors submitted around 11 000 models on 41 assembly targets. The
community demonstrated exceptional performance in overall fold and interface contact …

Continuous Automated Model EvaluatiOn (CAMEO)—Perspectives on the future of fully automated evaluation of structure prediction methods

X Robin, J Haas, R Gumienny… - Proteins: Structure …, 2021 - Wiley Online Library
Abstract The Continuous Automated Model EvaluatiOn (CAMEO) platform complements the
biennial CASP experiment by conducting fully automated blind evaluations of three …

Building structural models of a whole mycoplasma cell

M Maritan, L Autin, J Karr, MW Covert, AJ Olson… - Journal of molecular …, 2022 - Elsevier
Building structural models of entire cells has been a long-standing cross-discipline
challenge for the research community, as it requires an unprecedented level of integration …

Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment

MF Lensink, G Brysbaert, N Nadzirin… - Proteins: Structure …, 2019 - Wiley Online Library
We present the results for CAPRI Round 46, the third joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of 20 targets including 14 homo …

Assessment of the assessment—All about complexes

G Studer, G Tauriello, T Schwede - Proteins: Structure, Function …, 2023 - Wiley Online Library
Predicting model quality is a fundamental component of any modeling procedure, and blind
assessment of these methods constitutes a crucial aspect of the Critical Assessment of …

CASP15 cryo‐EM protein and RNA targets: Refinement and analysis using experimental maps

T Mulvaney, RC Kretsch, L Elliott… - Proteins: Structure …, 2023 - Wiley Online Library
CASP assessments primarily rely on comparing predicted coordinates with experimental
reference structures. However, experimental structures by their nature are only models …

Assessment of the CASP14 assembly predictions

B Ozden, A Kryshtafovych… - … : Structure, Function, and …, 2021 - Wiley Online Library
In CASP14, 39 research groups submitted more than 2500 3D models on 22 protein
complexes. In general, the community performed well in predicting the fold of the assemblies …