A design framework for optimized economic and inherently safe operation conditions for isoperibolic semi-batch reactors

J Zhu, L Hao, WS Bai, Z Zhu, B Zhang, H Wei - Process Safety and …, 2022 - Elsevier
Thermal runaway in the semi-batch reactors (SBRs) involving exothermic reaction can have
serious consequences and the primary driver of process design in the SBRs is economic …

Boundary diagrams safety criterion for liquid phase homogeneous semibatch reactors

KR Westerterp, M Lewak, EJ Molga - Industrial & Engineering …, 2014 - ACS Publications
In this work a summary of safety assessments based on a concept of boundary diagrams
safety criterion (BDSC) is given and adapted for liquid phase homogeneous reactions …

Kinetic-free safe optimization of a semibatch runaway reaction: nitration of 4-Chloro Benzotrifluoride

F Maestri, R Rota - Industrial & Engineering Chemistry Research, 2016 - ACS Publications
In this work the general Ψ number criterion for the safe operation of semibatch runaway
reactions has been applied to the optimization of a nitration process of primary importance in …

A new criterion to identify safe operating conditions for isoperibolic homogeneous semi-batch reactions

W Bai, L Hao, Z Guo, Y Liu, R Wang, H Wei - Chemical Engineering …, 2017 - Elsevier
The maximum temperature of a synthesis reaction (MTSR) is an important criterion for
process risk assessment and reactor design. In this paper, the variation of the dimensionless …

On the divergence criterion for runaway detection: Application to complex controlled systems

S Copelli, V Torretta, C Pasturenzi, M Derudi… - Journal of loss …, 2014 - Elsevier
It is well-known that, for certain values of the operative parameters influencing the dynamic
behavior of a chemical reactor, a phenomenon known as thermal runaway (that is, a loss of …

[HTML][HTML] Modeling of a solution polymerization reactor operating in semi-batch mode for polymethyl methacrylate production

F Sáez-Pardo, JJ Giner-Sanz… - … Research and Design, 2024 - Elsevier
The severe consequences of thermal runaways, make process optimization of paramount
importance for free radical polymerization reactors, in order to maximize in an integrated …

Classification and optimization of potentially runaway processes using topology tools

S Copelli, M Derudi, CS Cattaneo, G Nano… - Computers & chemical …, 2013 - Elsevier
Fast and strongly exothermic reactions can exhibit a well-known phenomenon called
“thermal runaway”. To identify high productivity and safe conditions for these reactions, with …

Modeling and process optimization of a full-scale emulsion polymerization reactor

S Copelli, M Barozzi, N Petrucci, VC Moreno - Chemical Engineering …, 2019 - Elsevier
One of the most common but promising processes for the production of paints and coatings
is the free radical emulsion polymerization reaction involving different types of monomers …

Comparative analysis of kinetic-free thermal runaway criteria for semi-batch isoperibolic homogeneous exothermic reaction

R Zhou, Y Chen, J Xu, J Jiang, C Bo - Journal of Thermal Analysis and …, 2024 - Springer
For the semi-batch isoperibolic homogeneous exothermic reaction, the dosing rate is an
effective method to control the exothermic rate. In this work, the esterification of propionic …

Investigation into maximum temperature of synthesis reaction and accumulation in isothermal semibatch processes

ZC Guo, L Hao, WS Bai, R Wang… - Industrial & Engineering …, 2015 - ACS Publications
Maximum temperature of synthesis reaction (MTSR), which is a function of the process
temperature (T p) and the maximum accumulation (X ac, max), is an important criterion for …