Iodinated contrast media (ICM) induced acute kidney injury (AKI) accounts for 11% of cases
of AKI and is its third most common cause in hospitalized patients. However, the …

There is growing evidence that oxidative stress contributes to hypertension. Oxidative stress
can precede the development of hypertension. In almost all models of hypertension, there is …

Hypertension is associated with an elevation of reactive oxygen species (ROS) and
frequently also with an impairment of endogenous antioxidant mechanisms. Experimental …

Heme oxygenase (HO) has been shown to be important for attenuating the overall
production of reactive oxygen species (ROS) through its ability to degrade heme and to …

Cellular injury or organ dysfunction from oxidative stress occurs when reactive oxygen
species (ROS) accumulate in excess of the host defense mechanisms. The deleterious effect …

Leptin is a 16-kDa protein secreted by white adipose tissue that is primarily involved in the
regulation of food intake and energy expenditure. Plasma leptin concentration is …

The goal of this study was to investigate water and solute transport, with a focus on sodium
transport (TNa) and metabolism along individual nephron segments under differing …

The present study examined whether chronic increased oxidative stress within the medulla
of the kidney lowers medullary blood flow and leads to hypertension. Optical fibers were …

We investigated the balance of free radicals in retinas at various time points after chronically
elevating intraocular pressures in rats. The left eyes of female Wistar rats were divided into …

Efficient oxygen utilization in the kidney may be supported by paracellular epithelial
transport, a form of passive diffusion that is driven by preexisting transepithelial …