The importance of pre-formulation studies and of 3D-printed nasal casts in the success of a pharmaceutical product intended for nose-to-brain delivery

L Deruyver, C Rigaut, P Lambert, B Haut… - Advanced drug delivery …, 2021 - Elsevier
This review aims to cement three hot topics in drug delivery:(a) the pre-formulation of new
products intended for nose-to-brain delivery;(b) the development of nasal casts for studying …

Cross-linked cyclodextrin glucanotransferase aggregates from Bacillus lehensis G1 for cyclodextrin production: Molecular modeling, developmental, physicochemical …

N Jailani, NR Jaafar, S Suhaimi, MM Mackeen… - International Journal of …, 2022 - Elsevier
Type of cross-linking agents influence the stability and active cross-linked enzyme
aggregates (CLEA) immobilization. The information of molecular interaction between …

The biological fate of pharmaceutical excipient β-cyclodextrin: Pharmacokinetics, tissue distribution, excretion, and metabolism of β-cyclodextrin in rats

K Mu, K Jiang, Y Wang, Z Zhao, S Cang, K Bi, Q Li… - Molecules, 2022 - mdpi.com
β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of
various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability …

Synthesis and characterization of thermosensitive hydrogel based on quaternized chitosan for intranasal delivery of insulin

AH Bahmanpour, M Ghaffari, PB Milan… - Biotechnology and …, 2021 - Wiley Online Library
Nasal administration is a form of systemic administration in which drugs are insufflated
through the nasal cavity. Steroids, nicotine replacement, antimigraine drugs, and peptide …

A review of recent advances in the estimation of pharmaceutical products using hydrophilic interaction chromatography (HILIC) technology

AK Fadhil, AS Rasheed, MJM Hassan - Egyptian Journal of …, 2023 - journals.ekb.eg
Liquid Chromatography as a separation tool has made significant strides in a systematic
study. The most widely used chromatographic process is reverse-phase liquid …

Active-electrode biosensor of SnO2 nanowire for cyclodextrin detection from microbial enzyme

CA Amorim, KC Blanco, IM Costa, EF Vicente… - …, 2020 - iopscience.iop.org
Cyclodextrin (CD) is a conical compound used in food and pharmaceutical industry to
complexation of hydrophobic substances. It is a product of microbial enzymes which …