The unique properties of IgG4 and its roles in health and disease
T Rispens, MG Huijbers - Nature Reviews Immunology, 2023 - nature.com
IgG4 is the least abundant subclass of IgG in human serum and has unique functional
features. IgG4 is largely unable to activate antibody-dependent immune effector responses …
features. IgG4 is largely unable to activate antibody-dependent immune effector responses …
International consensus statement on allergy and rhinology: Allergic rhinitis–2023
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
[PDF][PDF] Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
Food allergy: immune mechanisms, diagnosis and immunotherapy
W Yu, DMH Freeland, KC Nadeau - Nature Reviews Immunology, 2016 - nature.com
Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …
A biodiversity hypothesis
T Haahtela - Allergy, 2019 - Wiley Online Library
Biodiversity hypothesis states that contact with natural environments enriches the human
microbiome, promotes immune balance and protects from allergy and inflammatory …
microbiome, promotes immune balance and protects from allergy and inflammatory …
[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …
[HTML][HTML] Regulation of the host immune system by helminth parasites
RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …
mechanisms that affect all facets of the host immune response to ensure their persistence …
Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper
Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …
Efficacy of a house dust mite sublingual allergen immunotherapy tablet in adults with allergic asthma: a randomized clinical trial
Importance The house dust mite (HDM) sublingual allergen immunotherapy (SLIT) tablet is a
potential novel treatment option for HDM allergy–related asthma. Objectives To evaluate the …
potential novel treatment option for HDM allergy–related asthma. Objectives To evaluate the …
Food allergy and intolerance: A narrative review on nutritional concerns
D Gargano, R Appanna, A Santonicola… - Nutrients, 2021 - mdpi.com
Adverse food reactions include immune-mediated food allergies and non-immune-mediated
intolerances. However, this distinction and the involvement of different pathogenetic …
intolerances. However, this distinction and the involvement of different pathogenetic …