Nucleic acid amplification has permeated every field in the life sciences since the
introduction of the classic polymerase chain reaction (PCR) method in 1983. Yet, despite its …

Recombinase polymerase amplification (RPA) is a highly sensitive and selective isothermal
amplification technique, operating at 37–42° C, with minimal sample preparation and …

Recently, there has been a rapid progress in the development of techniques for isothermal
amplification of nucleic acids as an alternative to polymerase chain reaction (PCR). The …

Background Update diagnostic methods play essential roles in dealing with the current
global malaria situation and decreasing malaria incidence. Aim Global malaria control …

Introduction Recombinase polymerase amplification (RPA) is a promising and emerging
technology for rapidly amplifying target nucleic acid from minimally processed samples and …

Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Early disease detection through point-of-care (POC) testing is vital for quickly treating
patients and preventing the spread of harmful pathogens. Disease diagnosis is generally …

Potatoes are developed vegetatively from tubers, and therefore potato virus transmission is
always a possibility. The potato leafroll virus (PLRV) is a highly devastating virus of the …

Multiplexed isothermal amplification and detection of nucleic acid sequences and
biomarkers is of increasing importance in diverse areas including advanced diagnostics …

Since the introduction of the polymerase chain reaction (PCR) technique in 1983, nucleic
acid amplification has permeated all fields of biological science, particularly clinical …