Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib

N Cooper, W Ghanima, QA Hill, PLR Nicolson… - Platelets, 2023 - Taylor & Francis
Spleen tyrosine kinase (SYK) is an important regulatory molecule of signal transduction
pathways involved in the pathogenesis of autoimmune diseases such as immune …

Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

NS Taibe, MA Kord, MA Badawy… - Therapeutic …, 2022 - journals.sagepub.com
On 30 January 2020, the World Health Organization (WHO) declared the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic a public health emergency of …

Network-based drug repurposing identifies small molecule drugs as immune checkpoint inhibitors for endometrial cancer

F Ahmed, A Samantasinghar, W Ali, KH Choi - Molecular Diversity, 2024 - Springer
Endometrial cancer (EC) is the 6th most common cancer in women around the world. Alone
in the United States (US), 66,200 new cases and 13,030 deaths are expected to occur in …