[HTML][HTML] From antimicrobial to anticancer peptides. A review
D Gaspar, AS Veiga, MARB Castanho - Frontiers in microbiology, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …
organisms. Although AMPs have been essentially studied and developed as potential …
A systems biology view of blood vessel growth and remodelling
Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …
capillaries. This vascular network is not static, but instead dynamically remodels in response …
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis
Breast cancer metastasis involves lymphatic dissemination in addition to hematogenous
spreading. Although stromal lymphatic vessels (LVs) serve as initial metastatic routes, roles …
spreading. Although stromal lymphatic vessels (LVs) serve as initial metastatic routes, roles …
Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
Angiogenesis, the recruitment of new blood vessels, is a critical process for the growth,
expansion, and metastatic dissemination of developing tumors. Three types of cells make up …
expansion, and metastatic dissemination of developing tumors. Three types of cells make up …
Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis
Background Metastatic triple-negative breast cancer (TNBC) is a heterogeneous and
incurable disease. Numerous studies have been conducted to seek molecular targets to …
incurable disease. Numerous studies have been conducted to seek molecular targets to …
Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment
Tumour and organ microenvironments are crucial for cancer progression and metastasis.
Crosstalk between multiple non-malignant cell types in the microenvironments and cancer …
Crosstalk between multiple non-malignant cell types in the microenvironments and cancer …
Insect antimicrobial peptides: potential tools for the prevention of skin cancer
Antimicrobial peptides/proteins (AMPs) are biologically active molecules with diverse
structural properties that are produced by mammals, plants, insects, ticks, and …
structural properties that are produced by mammals, plants, insects, ticks, and …
Gene delivery nanoparticles to modulate angiogenesis
Angiogenesis is naturally balanced by many pro-and anti-angiogenic factors while an
imbalance of these factors leads to aberrant angiogenesis, which is closely associated with …
imbalance of these factors leads to aberrant angiogenesis, which is closely associated with …
[HTML][HTML] Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis
Triple negative breast cancer (TNBC) as a metastatic disease is currently incurable. Reliable
and reproducible methods for testing drugs against metastasis are not available. Stromal …
and reproducible methods for testing drugs against metastasis are not available. Stromal …
Lymphatic endothelial cells support tumor growth in breast cancer
Tumor lymphatic vessels (LV) serve as a conduit of tumor cell dissemination, due to their
leaky nature and secretion of tumor-recruiting factors. Though lymphatic endothelial cells …
leaky nature and secretion of tumor-recruiting factors. Though lymphatic endothelial cells …