Multiple sclerosis (MS) is a neurodegenerative disease characterized by a variable clinical
course and diverse pathophysiology, including nitrative and oxidative stresses as well as …

Obesity is a major public health issue resulting from an interaction between genetic and
environmental factors. Genetic risk scores (GRSs) are useful to summarize the effects of …

Abstract Type 2 diabetes (T2D) is defined by high levels of glucose in the blood. The
collagen IV level is associated with conditions of hyperglycemia and insulin resistance …

Background: Keratoconus (KC) is a degenerative eye disease which results from thinning of
the cornea and causes vision distortion. Oxidative stress damage to KC corneas may be …

Genome‐wide association studies indicated that hematopoietically‐expressed homeobox
(HHEX) gene is a remarkable candidate for type 2 diabetes (T2D) mellitus susceptibility in …

Infertility is a multifactorial and polygenic disease. A vast majority of infertility is still
unexplained despite modern diagnostic techniques. Oxidative stress is considered a factor …

Abstract β 1-Adrenegic receptor (ADRB-1) leads to increase both renin and ghrelin
secretions which are considered to be two hormones associated with type 2 diabetes …

Type 2 diabetes mellitus (T2D) as an important metabolic disorder is accompanied by
dysregulation in lipid metabolism. Sterol regulatory element-binding factor-2 (SREBF-2) …

Background Elevated oxidative stress plays a significant role in pathophysiology of
keratoconus (KC). Polymorphisms of the antioxidant enzymes as CAT and GPX‐1 might …

Introduction Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized
by persistent hyperglycemia, which results in initiates oxidative stress and disrupts various …