Inflammatory processes are prominent in various types of human and experimental
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …

Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary dysfunctional disease,
characterized by progressive vascular remodeling. Inflammation is an increasingly …

Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …

Objective: To evaluate the coagulative/fibrinolytic cascade and the circulating markers of the
endothelial injury in systemic sclerosis (SSc). Method: Plasma was obtained from 29 …

Altered immunity and inflammation are increasingly recognized features of pulmonary
arterial hypertension (PAH). This is suggested by infiltration of various inflammatory cells …

The prevalence of auto-antibodies associated to pulmonary arterial hypertension in
scleroderma patients was reviewed, based on reports cited in two major scientific …

Pulmonary arterial hypertension is a life threatening complication of several connective
tissue diseases including scleroderma (both diffuse and limited scleroderma, or the CREST …

Pulmonary arterial hypertension (PAH) may complicate diverse connective tissue diseases
(CTDs). Approximately 10% of patients with systemic sclerosis develop PAH, the prevalence …

Autoantibodies in systemic sclerosis are associated with demographic, diagnostic,
pathological, and prognostic features of the disease. Emerging research on the pathogenic …

Analyses of immunity in pulmonary arterial hypertension (PAH) support the notion that
maladaptation of the immune response exists. Altered immunity is an increasingly …