Copper has been used as an antimicrobial agent long time ago. Nowadays, copper-
containing nanoparticles (NPs) with antimicrobial properties have been widely used in all …

Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2) and
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …

Copper (Cu) is a bioelement essential for a myriad of enzymatic reactions, which when
present in high concentration leads to cytotoxicity. Whereas Cu toxicity is usually assumed to …

Background Both essential trace elements selenium (Se) and copper (Cu) play an important
role in maintaining brain function. Homeostasis of Cu, which is tightly regulated under …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder first described in
1906 that is currently estimated to impact∼ 40 million people worldwide. Extensive research …

Copper (Cu) is an essential, yet potentially toxic nutrient, as illustrated by inherited diseases
of copper deficiency and excess. Elevated expression of the ATP7A Cu exporter is known to …

Increased copper (Cu) and iron (Fe) levels in liver and brain are associated to oxidative
stress and damage with increased phospholipid oxidation process. The aim of this work was …

Homeostasis, a balance state in cells, is crucial for proper cellular function, growth, and long-
term survival. Otherwise, imbalanced homeostasis fosters many diseases. Specifically …

STUDY HYPOTHESIS Are the placental aquaporins (AQPs) involved in the apoptosis of
human trophoblast? STUDY FINDING The general blocking of placental AQPs with HgCl2 …

Toxic metals cause neurodegeneration via formation of toxic complexes with the cellular
compounds and production of highly reactive oxygen species. The present study aimed to …