Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Understanding interactions between biomaterials and biological systems using proteomics

Z Othman, BC Pastor, S van Rijt, P Habibovic - Biomaterials, 2018 - Elsevier
The role that biomaterials play in the clinical treatment of damaged organs and tissues is
changing. While biomaterials used in permanent medical devices were required to passively …

Automated, parallel mass spectrometry imaging and structural identification of lipids

SR Ellis, MRL Paine, GB Eijkel, JK Pauling, P Husen… - Nature …, 2018 - nature.com
We report a method that enables automated data-dependent acquisition of lipid tandem
mass spectrometry data in parallel with a high-resolution mass spectrometry imaging …

Cellular resolution in clinical MALDI mass spectrometry imaging: the latest advancements and current challenges

K Ščupáková, B Balluff, C Tressler… - Clinical Chemistry and …, 2020 - degruyter.com
Mass spectrometry (MS) is the workhorse of metabolomics, proteomics and lipidomics. Mass
spectrometry imaging (MSI), its extension to spatially resolved analysis of tissues, is a …

Perspective on advances in laser-based high-resolution mass spectrometry imaging

T Wang, X Cheng, H Xu, Y Meng, Z Yin, X Li… - Analytical …, 2019 - ACS Publications
Mass spectrometry imaging (MSI) has become a powerful tool in diverse fields, such as
chemistry, physics, materials, and life science. Although such research is getting more …

Next‐generation pathology practices with mass spectrometry imaging

HH Chung, P Huang, CL Chen, C Lee… - Mass Spectrometry …, 2023 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful technique that reveals the spatial distribution
of various molecules in biological samples, and it is widely used in pathology‐related …

On-tissue dataset-dependent MALDI-TIMS-MS2 bioimaging

S Heuckeroth, A Behrens, C Wolf, A Fütterer… - Nature …, 2023 - nature.com
Trapped ion mobility spectrometry (TIMS) adds an additional separation dimension to mass
spectrometry (MS) imaging, however, the lack of fragmentation spectra (MS2) impedes …

Preparing ductal epithelial organoids for high-spatial-resolution molecular profiling using mass spectrometry imaging

B Bakker, RDW Vaes, MR Aberle, T Welbers… - Nature …, 2022 - nature.com
Organoid culture systems are self-renewing, three-dimensional (3D) models derived from
pluripotent stem cells, adult derived stem cells or cancer cells that recapitulate key molecular …

Small molecule MALDI MS imaging: Current technologies and future challenges

PJ Trim, MF Snel - Methods, 2016 - Elsevier
Imaging of specific small molecules is particularly challenging using conventional optical
microscopy techniques. This has led to the development of alternative imaging modalities …

Recent advances in mass spectrometry analysis of neuropeptides

A Phetsanthad, NQ Vu, Q Yu… - Mass spectrometry …, 2023 - Wiley Online Library
Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …