Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

Understanding how organisms establish their form during embryogenesis and regeneration
represents a major knowledge gap in biological pattern formation. It has been recently …

Analysing the properties of a biological system through in silico experimentation requires a
satisfactory mathematical representation of the system including accurate values of the …

Large amounts of lipidomics data are rapidly becoming available. However, there is a lack of
tools capable of taking the full advantage of the wealth of new information. Lipid …

In this work we present Bio-PEPA, a process algebra for the modelling and the analysis of
biochemical networks. It is a modification of PEPA, originally defined for the performance …

We give a description of a Petri net-based framework for modelling and analysing
biochemical pathways, which unifies the qualitative, stochastic and continuous paradigms …

This year we celebrate the 150th anniversary of the law of mass action. This law is often
assumed to have been “there” forever, but it has its own history, background, and a definite …

Background Mathematical models provide abstract representations of the information
gained from experimental observations on the structure and function of a particular …

A First Course in Systems Biology is an introduction for advanced undergraduate and
graduate students to the growing field of systems biology. Its main focus is the development …

Like engineering systems, biological systems must also operate effectively in the presence
of internal and external uncertainty—such as genetic mutations or temperature changes, for …