Multiplexed profiling of extracellular vesicles for biomarker development

C Jiang, Y Fu, G Liu, B Shu, J Davis, GK Tofaris - Nano-micro letters, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …

Exosomal microRNA profiling

N Rahimian, JS Nahand, MR Hamblin… - … profiling: methods and …, 2022 - Springer
Exosomes are extracellular vesicles, which have the ability to convey various types of cargo
between cells. Lately, a great amount of interest has been paid to exosomal microRNAs …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

[HTML][HTML] Screening for lung cancer in individuals who never smoked: an international association for the study of lung cancer early detection and screening committee …

A Kerpel-Fronius, M Tammemägi, M Cavic… - Journal of Thoracic …, 2022 - Elsevier
Screening with low-dose computed tomography of high-risk individuals with a smoking
history reduces lung cancer mortality. Current screening guidelines and eligibility criteria …

A tale of exosomes and their implication in cancer

A Mishra, PS Bharti, N Rani, F Nikolajeff… - Biochimica et Biophysica …, 2023 - Elsevier
Cancer is a cause of high deaths worldwide and also a huge burden for the health system.
Cancer cells have unique properties such as a high rate of proliferation, self-renewal …

Status quo of Extracellular Vesicle isolation and detection methods for clinical utility

KS Visan, LY Wu, S Voss, A Wuethrich… - Seminars in Cancer …, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-sized particles that hold tremendous potential in the
clinical space, as their biomolecular profiles hold a key to non-invasive liquid biopsy for …

DNA barcode-based detection of exosomal microRNAs using nucleic acid lateral flow assays for the diagnosis of colorectal cancer

S Kim, J Han, JS Park, JH Kim, ES Lee, BS Cha… - Talanta, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related deaths worldwide. The standard methods for diagnosing CRC, endoscopy …

Recent advances in cell membrane camouflage-based biosensing application

X Yu, L Sha, Q Liu, Y Zhao, H Fang, Y Cao… - Biosensors and …, 2021 - Elsevier
Cell membrane, a semi-permeable membrane composed of phospholipid bilayers, is a
natural barrier to prevent extracellular substances from freely entering the cell. Cell …

[HTML][HTML] Medical diagnostic value of digital PCR (dPCR): A systematic review

S Nazir - Biomedical Engineering Advances, 2023 - Elsevier
Digital polymerase chain reaction (dPCR) is an emerging technique for the absolute
quantification of target nucleic acids. dPCR got attention as a precise quantification tool in …

Research advances for exosomal miRNAs detection in biosensing: From the massive study to the individual study

Y Wu, Y Zhang, X Zhang, S Luo, X Yan, Y Qiu… - Biosensors and …, 2021 - Elsevier
Exosomal miRNAs (exo-miRNAs) derived from cancer cell play a vital role in cancer
development and can be considered as a potential biomarker for cancer diagnostic …