Mice remain the most studied animal model in pancreas research. Since the findings of this
research are typically extrapolated to humans, it is important to understand both similarities …

A wealth of data and comprehensive reviews exist on pancreas development in mammals,
primarily mice, and other vertebrates. By contrast, human pancreatic development has been …

INTRODUCTION Early mammalian development requires the formation of embryonic and
extraembryonic tissues and a highly coordinated partnership between them. This close …

Pancreas oganogenesis comprises a coordinated and highly complex interplay of signaling
events and transcriptional networks that guide a step‐wise process of organ development …

The pancreas is an essential organ for proper nutrient metabolism and has both endocrine
and exocrine function. In the past two decades, knowledge of how the pancreas develops …

Context: Insulin resistance can be compensated by increased functional pancreatic β-cell
mass; otherwise, diabetes ensues. Such compensation depends not only on environmental …

The pancreas is an endoderm-derived glandular organ that participates in the regulation of
systemic glucose metabolism and food digestion through the function of its endocrine and …

Epithelial branch elongation is a central developmental process during branching
morphogenesis in diverse organs. This fundamental growth process into large arborized …

The pancreas is a complex organ comprised of three critical cell lineages: islet (endocrine),
acinar, and ductal. This review will focus upon recent insights and advances in the biology of …

Pancreatic multipotent progenitor cells (MPCs) produce acinar, endocrine and duct cells
during organogenesis, but their existence and location in the mature organ remain …