Per-and polyfluoroalkyl substances (PFAS) are a group of over 4700 heterogeneous
compounds with amphipathic properties and exceptional stability to chemical and thermal …

Per-and polyfluoroalkyl substances (PFAS) represent a group of synthetic compounds
widely used in industry plants due to their low grade of degradation, surfactant properties …

The thyroid gland regulates most of the physiological processes. Environmental factors,
including climate change, pollution, nutritional changes, and exposure to chemicals, have …

Sites impacted by aqueous film-forming foam (AFFF) contain co-contaminants that can
stimulate biotransformation of polyfluoroalkyl substances. Here, we compare how microbial …

Perfluorooctanesulfonic acid (PFOS) is a persistent anthropogenic chemical that can affect
the thyroid hormone system in humans and animals. In adults, thyroid hormones (THs) are …

Synthetic chemicals with endocrine disrupting properties are pervasive in the environment
and are present in the bodies of humans and wildlife. As thyroid hormones (THs) control …

Objectives To investigate the association of exposure to per-and polyfluoroalkyl substances
(PFAS) during early pregnancy with markers of the maternal thyroid system. Methods Serum …

A number of xenobiotics interfere with thyroid hormone (TH) signaling. Although adequate
supplies of TH are necessary for normal brain development, regulatory reliance on serum …

This review summarises the current state of knowledge regarding the physiology and control
of production of thyroid hormones, the effects of chemicals in perturbing their synthesis and …

Prenatal exposure to per-and polyfluorinated substances (PFAS) may impair fetal growth.
Our knowledge of the underlying mechanisms is incomplete. We used the Adverse Outcome …