When the production of reactive oxygen species (ROS) is overloaded surpassing the
capacity of the reductive rheostat, mammalian cells undergo a series of oxidative damage …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Current treatment options for foot ulcers, a serious and prevalent complication of diabetes,
remain nonspecific. In this Perspective, we present recent advances in understanding the …

Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

INTRODUCTION Fibroblasts produce extracellular matrix (ECM) molecules that regulate
tissue strength and resilience. Imbalanced ECM maintenance leads to tissue dysfunction …

Skin and intestinal epithelial barriers play a pivotal role in protecting underlying tissues from
harsh external environments. The protective role of these epithelia is, in part, dependent on …

The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Cinnamon essential oil is known to have antioxidant and antibacterial properties, which may
accelerate, wound healing. This study was conducted to evaluate the effects of an ointment …

Cutaneous wounds are a growing global health burden as a result of an aging population
coupled with increasing incidence of diabetes, obesity, and cancer. Cell-based approaches …