Hepatitis B virus (HBV), an enveloped partially double-stranded DNA virus, is a widespread
human pathogen responsible for more than 250 million chronic infections worldwide …

With a yearly death toll of 880,000, hepatitis B virus (HBV) remains a major health problem
worldwide, despite an effective prophylactic vaccine and well-tolerated, effective antivirals …

Conclusions HBV cccDNA minichromosomes in distinct epigenetic transcriptional states
showed a similar reduction rate during cell division but significantly differed in their …

As new pathogens emerge, new challenges must be faced. This is no different in infectious
disease research, where identifying the best tools available in laboratories to conduct an …

Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is
the causative agent of acute and chronic hepatitis. HBV can resist immune system …

Inflammation is a major contributor to the pathogenesis of almost all liver diseases. Low-
molecular-weight proteins called chemokines are the main drivers of liver infiltration by …

Acylcarnitines play an essential role in regulating the balance of intracellular sugar and lipid
metabolism. They serve as carriers to transport activated long-chain fatty acids into …

The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …

Background & Aims The persistence of covalently closed circular DNA (cccDNA) in infected
hepatocytes is the major barrier preventing viral eradication with existing therapies in …

About 250 million people worldwide are chronically infected with Hepatitis B virus (HBV),
contributing to a large burden on public health. Despite the existence of vaccines and …